Abstract
Murine models of rheumatoid arthritis are widely used for mechanistic studies and for the validation of therapeutic targets. Many models exist and can be classified into induced and spontaneous types. Even though models vary considerably in the pathogenesis of lesions, overlapping spectra of morphological features render the commonly used models suitable for standard histopathological examination and scoring strategies.
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Caplazi, P., Diehl, L. (2014). Histopathology in Mouse Models of Rheumatoid Arthritis. In: Potts, S., Eberhard, D., Wharton, Jr., K. (eds) Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development. Methods in Pharmacology and Toxicology. Humana Press, New York, NY. https://doi.org/10.1007/7653_2014_20
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DOI: https://doi.org/10.1007/7653_2014_20
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