Jorge Cervós-Navarro 1930–2021 Gisela Stoltenburg-DidingerHans-Hilmar Goebel Obituary Open access 23 July 2022 Pages: 391 - 392
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex Evelien Van SchoorSimona OspitalieriDietmar Rudolf Thal Original Paper 22 July 2022 Pages: 393 - 411
Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis Florian KrachEmily C. WheelerBeate Winner Original Paper Open access 01 July 2022 Pages: 413 - 435
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD Claudia S. BauerRebecca N. CohenKurt J. De Vos Original Paper Open access 25 July 2022 Pages: 437 - 464
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS Elke BraemsValérie BercierLudo Van Den Bosch Original Paper Open access 27 July 2022 Pages: 465 - 488
Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention Pablo Botella LucenaSarah VanherleIlse Dewachter Original Paper Open access 07 July 2022 Pages: 489 - 508
Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease Grace I. HallinanKadir A. OzcanRuben Vidal Original Paper Open access 12 July 2022 Pages: 509 - 520
Decreased FAK activity and focal adhesion dynamics impair proper neurite formation of medium spiny neurons in Huntington's disease Hae Nim LeeSeung Jae HyeonJihye Seong Original Paper 20 July 2022 Pages: 521 - 536
X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition Jonathan R. VolpattiMehdi M. Ghahramani-SenoJames J. Dowling Original Paper Open access 17 July 2022 Pages: 537 - 563
Single-cell DNA sequencing identifies risk-associated clonal complexity and evolutionary trajectories in childhood medulloblastoma development Marina DanilenkoMasood ZakaSteven C. Clifford Original Paper Open access 13 July 2022 Pages: 565 - 578
Intratumor and informatic heterogeneity influence meningioma molecular classification Harish N. VasudevanAbrar ChoudhuryDavid R. Raleigh Correspondence 27 June 2022 Pages: 579 - 583
The Alzheimer’s disease GWAS risk alleles in the ABCA7 promoter and 5’ region reduce ABCA7 expression Nicholas N. LyssenkoXinghua ShiDomenico Praticò Correspondence 27 June 2022 Pages: 585 - 587
Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer’s dementia Diego Sepulveda-FallaJustin S. SanchezYakeel T. Quiroz Case Report Open access 15 July 2022 Pages: 589 - 601