Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases Elena PerenthalerAnita NikoncukTahsin Stefan Barakat Original Paper Open access 09 December 2019 Pages: 415 - 442
Human subiculo-fornico-mamillary system in Alzheimer’s disease: Tau seeding by the pillar of the fornix Manon ThierrySusana BoludaCharles Duyckaerts Original Paper 10 December 2019 Pages: 443 - 461
Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer’s disease Marta J. KoperEvelien Van SchoorDietmar Rudolf Thal Original Paper 04 December 2019 Pages: 463 - 484
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease Charles E. EvansJames S. MinersPatrick G. Kehoe Original Paper Open access 25 January 2020 Pages: 485 - 502
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins Grant T. CorbettZemin WangDominic M. Walsh Original Paper Open access 18 December 2019 Pages: 503 - 526
Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions Patricia Aguilar-CalvoAlejandro M. SevillanoChristina J. Sigurdson Original Paper 31 October 2019 Pages: 527 - 546
Antibody signatures in patients with histopathologically defined multiple sclerosis patterns Lidia StorkDavid EllenbergerImke Metz Original Paper Open access 16 January 2020 Pages: 547 - 564
POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, α-dystroglycan hypoglycosylation and a distinctive radiological pattern E. Servián-MorillaM. Cabrera-SerranoCarmen Paradas Original Paper 03 January 2020 Pages: 565 - 582
Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker Andrey KorshunovKonstantin OkonechnikovAndreas von Deimling Original Paper 28 November 2019 Pages: 583 - 596
Loss of H3K27 trimethylation by immunohistochemistry is frequent in oligodendroglioma, IDH-mutant and 1p/19q-codeleted, but is neither a sensitive nor a specific marker Melike PekmezciJoanna J. PhillipsArie Perry Correspondence 07 January 2020 Pages: 597 - 600
Tectal glioma harbors high rates of KRAS G12R and concomitant KRAS and BRAF alterations Jason ChiangXiaoyu LiDavid W. Ellison Correspondence 10 December 2019 Pages: 601 - 602
cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas Daniel J. BratKenneth AldapeMichael Weller Correspondence 29 January 2020 Pages: 603 - 608