Emerging concepts in neurodegenerative diseases

ISSN: 2045-3701 (Online)

In this topical collection (22 articles)

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  1. Review

    Genetically modified large animal models for investigating neurodegenerative diseases

    Weili Yang, Xiusheng Chen, Shihua Li, Xiao-Jiang Li Article:218
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  2. Review

    Autophagy deficiency in neurodevelopmental disorders

    Zhiqiang Deng, Xiaoting Zhou, Jia-Hong Lu, Zhenyu Yue Article:214
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  3. Research

    Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology

    Guilherme Povala, Bruna Bellaver, Marco Antônio De Bastiani… Article:204
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  4. Review

    α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox

    Christopher Simon, Tomoko Soga, Hirotaka James Okano, Ishwar Parhar Article:196
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  5. Review

    Parkinson's in the bone

    Lei Xiong, Jin-Xiu Pan, Hao-han Guo, Lin Mei, Wen-Cheng Xiong Article:190
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  6. Review

    Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases

    Shuqi Du, Hui Zheng Article:188
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  7. Review

    Common immunopathogenesis of central nervous system diseases: the protein-homeostasis-system hypothesis

    Kyung-Yil Lee Article:184
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  8. Review

    Current knowledge and challenges associated with targeted delivery of neurotrophic factors into the central nervous system: focus on available approaches

    Gozal Bahlakeh, Reza Rahbarghazi, Daruosh Mohammadnejad, Ali Abedelahi… Article:181
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  9. Research

    Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene

    Hui Tian, Yanwen Jiao, Mingyue Guo, Yilin Wang, Ruiqi Wang, Cao Wang… Article:166
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  10. Research

    A change of PD-1/PD-L1 expression on peripheral T cell subsets correlates with the different stages of Alzheimer's Disease

    Ching-Tse Wu, Cheng-I Chu, Feng-Yu Wang, Hui-Yu Yang, Wei-Sung Tseng… Article:162
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  11. Review

    Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

    Morteza Heidarzadeh, Yasemin Gürsoy-Özdemir, Mehmet Kaya… Article:142
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  12. Research

    Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway

    Cheong-Meng Chong, Yuan Tan, Jiaqi Tong, Minjing Ke, Ke Zhang… Article:131
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  13. Review

    Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases

    Danying Yang, Xifeng Wang, Lieliang Zhang, Yang Fang, Qingcui Zheng… Article:106
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  14. Research

    Metabolomics of blood reveals age-dependent pathways in Parkinson’s Disease

    Nicola D’Ascenzo, Emanuele Antonecchia, Antonella Angiolillo… Article:102
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  15. Research

    Microglia degrade Tau oligomers deposit via purinergic P2Y12-associated podosome and filopodia formation and induce chemotaxis

    Subashchandrabose Chinnathambi, Rashmi Das Article:95
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  16. Review

    Post-synaptic specialization of the neuromuscular junction: junctional folds formation, function, and disorders

    Suqi Zou, Bing-Xing Pan Article:93
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  17. Research

    Siah-1-interacting protein regulates mutated huntingtin protein aggregation in Huntington’s disease models

    Ewelina Latoszek, Małgorzata Wiweger, Jan Ludwiczak… Article:34
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  18. Research

    Causal association evaluation of diabetes with Alzheimer's disease and genetic analysis of antidiabetic drugs against Alzheimer's disease

    Lei Meng, Zhe Wang, Hong-Fang Ji, Liang Shen Article:28
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  19. Research

    The common incidence-age multistep model of neurodegenerative diseases revisited: wider general age range of incidence corresponds to fewer disease steps

    Daniela Gerovska, Marcos J. Araúzo-Bravo Article:11
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  20. Review

    Small molecule modulators of chromatin remodeling: from neurodevelopment to neurodegeneration

    Dongfang Jiang, Tingting Li, Caixia Guo, Tie-Shan Tang, Hongmei Liu Article:10
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