Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
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Volume 19, issue 1, December 2018
229 articles in this issue
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dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
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Diversification and independent domestication of Asian and European pears
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Tensorial blind source separation for improved analysis of multi-omic data
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Hundreds of novel composite genes and chimeric genes with bacterial origins contributed to haloarchaeal evolution
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MICMIC: identification of DNA methylation of distal regulatory regions with causal effects on tumorigenesis
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A major locus controls local adaptation and adaptive life history variation in a perennial plant
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UMI-count modeling and differential expression analysis for single-cell RNA sequencing
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Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
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RNA m6A methylation participates in regulation of postnatal development of the mouse cerebellum
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Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome
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SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology
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An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray
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On the journey from nematode to human, scientists dive by the zebrafish cell lineage tree
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Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells
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Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
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Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion
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The hypothesis of ultraconserved enhancer dispensability overturned
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FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map
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Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish
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OCEAN-C: mapping hubs of open chromatin interactions across the genome reveals gene regulatory networks
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Gene-level differential analysis at transcript-level resolution
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Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations
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Recent advances in plant and animal genomics are taking agriculture to new heights
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Mapping human pluripotent stem cell differentiation pathways using high throughput single-cell RNA-sequencing
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Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing
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QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data
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Discovery of physiological and cancer-related regulators of 3′ UTR processing with KAPAC
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Distinctive epigenomes characterize glioma stem cells and their response to differentiation cues
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Pulling the genome in opposite directions to dissect gene networks
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SUPPA2: fast, accurate, and uncertainty-aware differential splicing analysis across multiple conditions
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Comparison and optimization of CRISPR/dCas9/gRNA genome-labeling systems for live cell imaging
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FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
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ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues
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The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts
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Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
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Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data
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Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci
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Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesis
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