Genetic disease risks can be misestimated across global populations
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Volume 19, issue 1, December 2018
229 articles in this issue
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Bottlenecks for genome-edited crops on the road from lab to farm
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CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
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Alternative polyadenylation factors link cell cycle to migration
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Comparative genomics reveals the distinct evolutionary trajectories of the robust and complex coral lineages
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Canonical and single-cell Hi-C reveal distinct chromatin interaction sub-networks of mammalian transcription factors
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PINES: phenotype-informed tissue weighting improves prediction of pathogenic noncoding variants
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Chromosome-level assembly reveals extensive rearrangement in saker falcon and budgerigar, but not ostrich, genomes
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Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing
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CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis
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Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial
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Chromosome evolution at the origin of the ancestral vertebrate genome
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RefSeq database growth influences the accuracy of k-mer-based lowest common ancestor species identification
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CRISPR-induced exon skipping is dependent on premature termination codon mutations
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A comparative study of endoderm differentiation in humans and chimpanzees
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SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation
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CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops
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CRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens
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PHLI-seq: constructing and visualizing cancer genomic maps in 3D by phenotype-based high-throughput laser-aided isolation and sequencing
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Modularity of genes involved in local adaptation to climate despite physical linkage
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Evolutionary and developmental dynamics of sex-biased gene expression in common frogs with proto-Y chromosomes
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Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes
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A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1
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The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions
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A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains
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Manipulating plant RNA-silencing pathways to improve the gene editing efficiency of CRISPR/Cas9 systems
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Ankyrin domain encoding genes from an ancient horizontal transfer are functionally integrated into Nasonia developmental gene regulatory networks
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ABLE: blockwise site frequency spectra for inferring complex population histories and recombination
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Dynamics and functional interplay of histone lysine butyrylation, crotonylation, and acetylation in rice under starvation and submergence
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Continuity of transcriptomes among colorectal cancer subtypes based on meta-analysis
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BayesCCE: a Bayesian framework for estimating cell-type composition from DNA methylation without the need for methylation reference
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Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations
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Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation
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All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo
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Origin of exon skipping-rich transcriptomes in animals driven by evolution of gene architecture
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Alternative splicing links histone modifications to stem cell fate decision
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Reduced intrinsic DNA curvature leads to increased mutation rate
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Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity
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