Brain Barriers and their Microenvironment: Emerging Models and Techniques

In this topical collection (14 articles)

1. Study protocol

   A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice

   Yasuo Uchida, Masanori Tachikawa, Wataru Obuchi… Article:21

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2. Review

   The hCMEC/D3 cell line as a model of the human blood brain barrier

   Babette Weksler, Ignacio A Romero, Pierre-Olivier Couraud Article:16

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3. Study protocol

   Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging

   Wandong Zhang, Huaqi Xiong, Debbie Callaghan, Hong Liu… Article:13

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4. Review

   The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects

   Elizabeth CM de Lange Article:12

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5. Study protocol

   Organotypic brain slices: a model to study the neurovascular unit micro-environment in epilepsies

   Mélanie Morin-Brureau, Frédéric De Bock… Article:11

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6. Review

   Studies on the human choroid plexus in vitro

   Zoran B Redzic Article:10

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7. Review

   Quantitative imaging assessment of blood-brain barrier permeability in humans

   Yoash Chassidim, Ronel Veksler, Svetlana Lublinsky… Article:9

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8. Study protocol

   Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo

   Caroline Coisne, Ruth Lyck, Britta Engelhardt Article:7

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9. Study protocol

   The brain slice method for studying drug distribution in the CNS

   Irena Loryan, Markus Fridén, Margareta Hammarlund-Udenaes Article:6

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10. Review

    Impedance-based cell monitoring: barrier properties and beyond

    Kathrin Benson, Sandra Cramer, Hans-Joachim Galla Article:5

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11. Research

    Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells

    Arsalan S Haqqani, Christie E Delaney… Article:4

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12. Review

    Genetic mouse models to study blood–brain barrier development and function

    Fabien Sohet, Richard Daneman Article:3

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13. Review

    Modeling the blood–brain barrier using stem cell sources

    Ethan S Lippmann, Abraham Al-Ahmad, Sean P Palecek… Article:2

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14. Study protocol

    Culture models to study leukocyte trafficking across the choroid plexus

    Tobias Tenenbaum, Ulrike Steinmann, Corinna Friedrich… Article:1

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