Human and rodent genomics

ISSN: 1471-2164 (Online)

In this topical collection (1315 articles)

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  1. Research article

    A hyper-dynamic nature of bivalent promoter states underlies coordinated developmental gene expression modules

    Akshay Shah, Anja Oldenburg, Philippe Collas Article:1186
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  2. Research article

    Reproducibility enhancement and differential expression of non predefined functional gene sets in human genome

    Samoel RM da Silva, Gabriel C Perrone, João M Dinis, Rita MC de Almeida Article:1181
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  3. Research article

    CAGE-defined promoter regions of the genes implicated in Rett Syndrome

    Morana Vitezic, Nicolas Bertin, Robin Andersson, Leonard Lipovich… Article:1177
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  4. Research article

    Distinct gene signatures in aortic tissue from ApoE-/-mice exposed to pathogens or Western diet

    Carolyn D Kramer, Ellen O Weinberg, Adam C Gower, Xianbao He… Article:1176
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  5. Research article

    Quantification of epigenetic biomarkers: an evaluation of established and emerging methods for DNA methylation analysis

    Nicholas Redshaw, Jim F Huggett, Martin S Taylor, Carole A Foy… Article:1174
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  6. Methodology article

    Are special read alignment strategies necessary and cost-effective when handling sequencing reads from patient-derived tumor xenografts?

    Kai-Yuen Tso, Sau Dan Lee, Kwok-Wai Lo, Kevin Y Yip Article:1172
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  7. Research article

    Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells

    Philippe Nizard, Frédéric Ezan, Dominique Bonnier, Nolwenn Le Meur… Article:1169
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  8. Research article

    Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates

    Christian Selinger, Jennifer Tisoncik-Go, Vineet D Menachery… Article:1161
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  9. Research article

    Exome sequencing and genome-wide copy number variant mapping reveal novel associations with sensorineural hereditary hearing loss

    Rajini R Haraksingh, Fereshteh Jahanbani, Juan Rodriguez-Paris… Article:1155
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  10. Research article

    Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease

    Abhimanyu Krishna, Maria Biryukov, Christophe Trefois, Paul MA Antony… Article:1154
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  11. Methodology article

    Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

    Jesse D Riordan, Luke J Drury, Ryan P Smith, Benjamin T Brett… Article:1150
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  12. Research article

    Histone modifications involved in cassette exon inclusions: a quantitative and interpretable analysis

    Hui Liu, Ting Jin, Jihong Guan, Shuigeng Zhou Article:1148
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  13. Research article

    Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy

    Paul O’Reilly, Csaba Ortutay, Grainne Gernon, Enda O’Connell… Article:1144
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  14. Research article

    Evolutionarily emerged G tracts between the polypyrimidine tract and 3′ AG are splicing silencers enriched in genes involved in cancer

    Muhammad Sohail, Wenguang Cao, Niaz Mahmood, Mike Myschyshyn, Say Pham Hong… Article:1143
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  15. Research article

    Chromosome microarray testing for patients with congenital heart defects reveals novel disease causing loci and high diagnostic yield

    Juan Geng, Jonathan Picker, Zhaojing Zheng, Xiaoqing Zhang, Jian Wang… Article:1127
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  16. Methodology article

    A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data

    Young Jin Kim, Juyoung Lee, Bong-Jo Kim, Taesung Park Article:1109
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  17. Research article

    RNA-Seq gene expression profiling of HepG2 cells: the influence of experimental factors and comparison with liver tissue

    Alexander V Tyakht, Elena N Ilina, Dmitry G Alexeev, Dmitry S Ischenko… Article:1108
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  18. Research article

    Unbiased chromatin accessibility profiling by RED-seq uncovers unique features of nucleosome variants in vivo

    Poshen B Chen, Lihua J Zhu, Sarah J Hainer, Kurtis N McCannell… Article:1104
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  19. Research article

    Chronic binge alcohol administration dysregulates global regulatory gene networks associated with skeletal muscle wasting in simian immunodeficiency virus-infected macaques

    Liz Simon, Andrew D. Hollenbach, Jovanny Zabaleta, Patricia E. Molina Article:1097
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  20. Research article

    Genetic differences among ethnic groups

    Tao Huang, Yang Shu, Yu-Dong Cai Article:1093
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