Pharmacokinetic Analysis of Drug Absorption from Muscle Based on a Physiological Diffusion Model: Effect of Molecular Size on Absorption Eiji NaraMasaaki MasegiMitsuru Hashida OriginalPaper Pages: 161 - 168
An Experimental Design Strategy for Quantitating Complex Pharmacokinetic Models: Enterohepatic Circulation with Time-Varying Gallbladder Emptying as an Example Yow-Ming Chen WangRichard H. Reuning OriginalPaper Pages: 169 - 177
Potentiation of Cytotoxicity of Mitoxantrone Toward CHO-K1 Cells in Vitro by Dipyridamole Pankaj B. DesaiRajagopalan Sridhar OriginalPaper Pages: 178 - 181
A Novel Approach for the Determination of the Pain-Producing Potential of Intravenously Injected Substances in the Conscious Rat John M. MarcekWilliam J. SeamanRoyal J. Weaver OriginalPaper Pages: 182 - 186
Cutaneous Metabolism of Nitroglycerin in Vitro. I. Homogenized Versus Intact Skin Naruhito HigoRobert S. HinzRichard H. Guy OriginalPaper Pages: 187 - 190
Enhanced Bioavailability of Cefoxitin Using Palmitoyl L-Carnitine. I. Enhancer Activity in Different Intestinal Regions Steven C. SuttonEdward L. LeCluyseJoseph A. Fix OriginalPaper Pages: 191 - 194
Hydrophobic Anionic Gel Beads for Swelling-Controlled Drug Delivery Cherng-Ju KimPing I. Lee OriginalPaper Pages: 195 - 199
Biodegradable Pseudolatexes: The Chemical Stability of Poly(D,L-Lactide) and Poly (ε-Caprolactone) Nanoparticles in Aqueous Media Mark D. CoffinJames W. McGinity OriginalPaper Pages: 200 - 205
Development of Extended-Release Solid Dispersions of Nonsteroidal Antiinflammatory Drugs with Aqueous Polymeric Dispersions: Optimization of Drug Release via a Curve-Fitting Technique Chris HoGeorge Chiaw-Chi Hwang OriginalPaper Pages: 206 - 210
Determination of Lidocaine Concentrations in Skin After Transdermal Iontophoresis: Effects of Vasoactive Drugs J. Edmond RiviereNancy A. Monteiro-RiviereAlfred O. Inman OriginalPaper Pages: 211 - 214
An Electrically Modulated Drug Delivery Device. II. Effect of Ionic Strength, Drug Concentration, and Temperature Antony D'EmanueleJohn N. Staniforth OriginalPaper Pages: 215 - 219
Factors Affecting the Release Rate of Terbutaline from Liposome Formulations After Intratracheal Instillation in the Guinea Pig Robert M. FieldingRobert M. Abra OriginalPaper Pages: 220 - 223
Pharmacokinetic Evaluation of Drug Interactions with Anti-Human Immunotrophic Virus (HIV) Drugs. III. 2′,3′-Dideoxycytidine (ddC) and Zidovudine in Monkeys Mingxin QianAnne R. SwaglerJames M. Gallo OriginalPaper Pages: 224 - 227
Competitive Inhibition of Zidovudine Clearance by Probenecid During Continuous Coadministration Shekman L. WongMohsen A. HedayaRonald J. Sawchuk OriginalPaper Pages: 228 - 235
Effect of Chronic Hypertension on the Blood–Brain Barrier Permeability of Libenzapril Jian-ping TangAshok RakhitSrikumaran Melethil OriginalPaper Pages: 236 - 243
Bioavailability of Leuprolide Acetate Following Nasal and Inhalation Delivery to Rats and Healthy Humans Akwete AdjeiDean SundbergAlexander Chun OriginalPaper Pages: 244 - 249
Pharmaceutical Properties of Loracarbef: The Remarkable Solution Stability of an Oral 1-Carba-l-dethiacephalosporin Antibiotic Carol E. PasiniJoseph M. Indelicato OriginalPaper Pages: 250 - 254
Development and Evaluation of a Novel Dissolution Apparatus for Medicated Chewing Gum Products James N. RiderEd L. BrunsonAlan B. Jones OriginalPaper Pages: 255 - 259
Prolonged Systemic Delivery of Peptide Drugs by Long-Circulating Liposomes: Illustration with Vasopressin in the Brattleboro Rat Martin C. WoodleGert StormFrancis C. Szoka, Jr OriginalPaper Pages: 260 - 265
The Influence of Sucrose, Dextran, and Hydroxypropyl-β-cyclodextrin as Lyoprotectants for a Freeze-Dried Mouse IgG2a Monoclonal Antibody (MN12) Maaike E. RessingWim JiskootDaan J. A. Crommelin OriginalPaper Pages: 266 - 270
Renal Tubular Handling of p-Aminohippurate and Epidermal Growth Factor (EGF) in Filtering and Nonfiltering Perfused Rat Kidneys Dong-Chool KimYuichi SugiyamaManabu Hanano OriginalPaper Pages: 271 - 275
Colonic Drug Delivery: Enhanced Release of Indomethacin from Cross-Linked Chondroitin Matrix in Rat Cecal Content Abraham RubinsteinDavid NakarAmnon Sintov Note Pages: 276 - 278