Modeling of Pharmacokinetic/Pharmacodynamic (PK/PD) Relationships: Concepts and Perspectives Hartmut DerendorfBernd Meibohm ReviewPaper Pages: 176 - 185
Subject-by-Formulation Interaction in Determinations of Individual Bioequivalence: Bias and Prevalence Laszlo EndrenyiLaszlo Tothfalusi OriginalPaper Pages: 186 - 190
The Effect of Hormones on the Expression of Five Isoforms of UDP-Glucuronosyltransferase in Primary Cultures of Rat Hepatocytes Van Q. LiDavid A. PrenticePaul V. Desmond OriginalPaper Pages: 191 - 197
Liposomes with Incorporated MHC Class Il/Peptide Complexes as Antigen Presenting Vesicles for Specific T Cell Activation Annemiek J. M. L. van RensenMarca H. M. WaubenDaan J. A. Crommelin OriginalPaper Pages: 198 - 204
Prediction of Membrane Permeability to Peptides from Calculated Dynamic Molecular Surface Properties Patric StenbergKristina LuthmanPer Artursson OriginalPaper Pages: 205 - 212
Permeation of PEO-PBLA-FITC Polymeric Micelles in Aortic Endothelial Cells Jiahorng LiawTakao AoyagiTeruo Okano OriginalPaper Pages: 213 - 220
Net Secretion of Furosemide Is Subject to Indomethacin Inhibition, as Observed in Caco-2 Monolayers and Excised Rat Jejunum Shawn D. FlanaganLeslie Z. Benet OriginalPaper Pages: 221 - 224
Effects of Intestinal CYP3A4 and P-Glycoprotein on Oral Drug Absorption—Theoretical Approach Kiyomi ItoHiroyuki KusuharaYuichi Sugiyama OriginalPaper Pages: 225 - 231
Intracranial Delivery of Recombinant Nerve Growth Factor: Release Kinetics and Protein Distribution for Three Delivery Systems W. Mark SaltzmanMichele W. MakJeffrey L. Cleland OriginalPaper Pages: 232 - 240
The Acidic Microclimate in Poly(lactide-co-glycolide) Microspheres Stabilizes Camptothecins Anna ShenderovaThomas G. BurkeSteven P. Schwendeman OriginalPaper Pages: 241 - 248
Protein Inhalation Powders: Spray Drying vs Spray Freeze Drying Yuh-Fun MaaPhuong-Anh NguyenChung C. Hsu OriginalPaper Pages: 249 - 254
A Polysorbate-Based Non-Ionic Surfactant Can Modulate Loading and Release of β-Lactoglobulin Entrapped in Multiphase Poly(DL-Lactide-co-glycolide) Microspheres Judith RojasHuguette Pinto-AiphandaryElias Fattal OriginalPaper Pages: 255 - 260
Influence of Crystal Habit on Trimethoprim Suspension Formulation Ashok K. TiwaryGopal M. Panpalia OriginalPaper Pages: 261 - 265
Evaluation of the Feasibility and Use of a Prototype Remote Drug Delivery Capsule (RDDC) for Non-Invasive Regional Drug Absorption Studies in the GI Tract of Man and Beagle Dog Alan F. ParrErik P. SandeferGeorge A. Digenis OriginalPaper Pages: 266 - 271
The Effect of In Vivo Dissolution, Gastric Emptying Rate, and Intestinal Transit Time on the Peak Concentration and Area-Under-the-Curve of Drugs with Different Gastrointestinal Permeabilities Lydia C. KausWilliam R. GillespieGordon L. Amidon OriginalPaper Pages: 272 - 280
Enantioselective Synthesis and Pharmacological Evaluation of a New Type of Verapamil Analog with Hypotensive and Calcium Antagonist Activities Herbert L. HollandJian-Xin GuAndrew J. Willetts OriginalPaper Pages: 281 - 287
Pharmacokinetics of Aminolevulinic Acid After Intravesical Administration to Dogs James T. DaltonDiansong ZhouMarvin C. Meyer OriginalPaper Pages: 288 - 295
Enhanced Antinociception of the Model Opioid Peptide [D-Penicillamine2,5] Enkephalin by P-Glycoprotein Modulation Cuiping ChenGary M. Pollack OriginalPaper Pages: 296 - 301
Estimation of Intradermal Disposition Kinetics of Drugs: I. Analysis by Compartment Model with Contralateral Tissues Kazuki NakayamaHisae MatsuuraToshikiro Kimura OriginalPaper Pages: 302 - 308
Effects of Hyperlipidemia on the Pharmacokinetics of Nifedipine in the Rat Lise A. EliotRobert T. FosterFakhreddin Jamali OriginalPaper Pages: 309 - 313
Enhanced Accumulation of Sialyl Lewis X-Carboxymethylpullulan Conjugate in Acute Inflammatory Lesion Kazutoshi HorieMasahiro SakagamiTeruomi Ito OriginalPaper Pages: 314 - 320
Peptidoleukotriene (PLT) Release and Absorption from the Airways of the Isolated Perfused Guinea Pig Lung Following Chemical and Antigenic Challenge Rosemary A. KoveleskyPeter R. ByronJürgen Venitz OriginalPaper Pages: 321 - 326
Confocal Imaging of Peripheral Regions of Intact Rat Lungs Following Intratracheal Administration of 6-Carboxyfluorescein, FITC-insulin, and FITC-Dextran Roderike PohlRoger S. ThrallPaul A. Kramer OriginalPaper Pages: 327 - 332
A New Method for Dissolution Studies of Lipid-Filled Capsules Employing Nifedipine as a Model Drug Viness PillayReza Fassihi BriefCommunication Pages: 333 - 337