An Interview with a Distinguished Pharmaceutical Scientist: Joseph R. Robinson; To whom correspondence should be addressed at University of Wisconsin, School of Pharmacy, 425 N. Charter St., Madison, Wisconsin 53706-1515. Legacy Pages: 365 - 367
Recent Advances in Structure-Based Ligand Design Using Molecular Dynamics and Monte Carlo Methods Peter Kollman Commentary Pages: 368 - 370
Drug Exsorption from Blood into the Gastrointestinal Tract Kazuhiko ArimoriMasahiro Nakano ReviewPaper Pages: 371 - 376
Localized Delivery of Proteins in the Brain: Can Transport Be Customized? Michael F. HallerW. Mark Saltzman ReviewPaper Pages: 377 - 385
Advances and Challenges in the Prevention and Treatment of Alzheimer's Disease Roberta Diaz BrintonRose S. Yamazaki ReviewPaper Pages: 386 - 398
The Duration of Measuring Partial AUCs for the Assessment of Bioequivalence Laszlo EndrenyiFerenc CsizmadiaMei-Ling Chen OriginalPaper Pages: 399 - 404
Coverage and Precision of Confidence Intervals for Area Under the Curve Using Parametric and Non-parametric Methods in a Toxicokinetic Experimental Design Peter L. Bonate OriginalPaper Pages: 405 - 410
Possible Role of Anion Exchanger AE2 as the Intestinal Monocarboxylic Acid/Anion Antiporter Hikaru YabuuchiIkumi TamaiAkira Tsuji OriginalPaper Pages: 411 - 416
The Use of Pharmacoscintigraphy to Elucidate Food Effects Observed with a Novel Protease Inhibitor (Saquinavir) C. J. KenyonF. BrownI. R. Wilding OriginalPaper Pages: 417 - 422
Active Apical Secretory Efflux of the HIV Protease Inhibitors Saquinavir and Ritonavir in Caco-2 Cell Monolayers Jochem AlsenzHans SteffenRainer Alex OriginalPaper Pages: 423 - 428
Mechanism of Compound- and Species-Specific Food Effects of Structurally Related Antiarrhythmic Drugs, Disopyramide and Bidisomide Chyung S. CookLiming ZhangAziz Karim OriginalPaper Pages: 429 - 433
Stability of Alkoxycarbonylamidine Prodrugs Zahra ShahrokhEric LeeMichael F. Powell OriginalPaper Pages: 434 - 441
Influence of Different Fat Emulsion-Based Intravenous Formulations on the Pharmacokinetics and Pharmacodynamics of Propofol Eugene H. CoxCatherijne A. J. KnibbeMeindert Danhof OriginalPaper Pages: 442 - 448
Species Differences of Serum Albumins: II. Chemical and Thermal Stability Takamitsu KosaToru MaruyamaMasaki Otagiri OriginalPaper Pages: 449 - 454
Inhibition of Tracheal Vascular Extravasation by Liposome-Encapsulated Albuterol in Rats Weiming ZhangLuke GuoDemetrios Papahadjopoulos OriginalPaper Pages: 455 - 460
Effect of Dose and Release Rate on Pulmonary Targeting of Liposomal Triamcinolone Acetonide Phosphate Sandra SuarezRicardo J. Gonzalez-RothiGünther Hochhaus OriginalPaper Pages: 461 - 465
Development and Internal Validation of an In Vitro-in Vivo Correlation for a Hydrophilic Metoprolol Tartrate Extended Release Tablet Formulation Natalie D. EddingtonPatrick MarroumLarry Augsburger OriginalPaper Pages: 466 - 473
Pulsatile Drug Release from an Insoluble Capsule Body Controlled by an Erodible Plug Ina KrögelRoland Bodmeier OriginalPaper Pages: 474 - 481
Controlled Release Gel of Ibuprofen and Lidocaine in Epidural Use—Analgesia and Systemic Absorption in Pigs Anne PaavolaPekka TarkkilaPer Rosenberg OriginalPaper Pages: 482 - 487
Pharmacokinetics of Cocaine and Metabolites Following Intragastric Administration to Ten-Day-Old Rat Pups Nasser N. NyamweyaBill J. GurleyKim E. Light BriefCommunication Pages: 488 - 491
Stratum Corneum Thickness and Apparent Water Diffusivity: Facile and Noninvasive Quantitation In Vivo Fabrice PirotEnzo BerardescaRichard H. Guy BriefCommunication Pages: 492 - 494
Lipid Extracting Effect of Ethanol on Keratinized Oral Mucosa Adriana Ganem-QuintanarYves JacquesPierre Buri BriefCommunication Pages: 495 - 498
Negative Correlation of n-Octanol/ Water Partition Coefficient and Transport of Some Guanine Derivatives Through Rat Jejunum In Vitro Albin KristlJosef J. Tukker BriefCommunication Pages: 499 - 501
Modeling Mucoadhesion by Use of Surface Energy Terms Obtained by the Lewis Acid-Lewis Base Approach: III. An Interaction Between Teflon and Carbopol Graham BucktonMarco Montagno Cappuccinello BriefCommunication Pages: 502 - 503