News from the National Institute of General Medical Sciences (NIGMS) Rochelle M. Long News Pages: 1647 - 1648
Estimating the Critical Molecular Mobility Temperature (TK) of Amorphous Pharmaceuticals Bruno C. HancockKaren ChristensenSheri L. Shamblin Letter to the Editor Pages: 1649 - 1651
BBB Transport and P-glycoprotein Functionality Using MDR1A (-/-) and Wild-Type Mice. Total Brain Versus Microdialysis Concentration Profiles of Rhodamine-123 Elizabeth C. M. de LangeGertjan de BockDouwe D. Breimer OriginalPaper Pages: 1657 - 1665
In Vitro and In Situ Absorption of SDZ-RAD Using a Human Intestinal Cell Line (Caco-2) and a Single Pass Perfusion Model in Rats: Comparison with Rapamycin Andrew CroweMichel Lemaire OriginalPaper Pages: 1666 - 1672
Methodological Aspects of the Use of a Calibrator in In Vivo Microdialysis–Further Development of the Retrodialysis Method M. René BouwMargareta Hammarlund-Udenaes OriginalPaper Pages: 1673 - 1679
Effect of Ultrasound Application on Skin Metabolism of Prednisolone 21-Acetate Tomohiro HikimaYoshiaki HiraiKakuji Tojo OriginalPaper Pages: 1680 - 1683
Biotransformation of Estradiol in the Human Keratinocyte Cell Line HaCaT: Metabolism Kinetics and the Inhibitory Effect of Ethanol Ralf AltenburgerThomas Kissel OriginalPaper Pages: 1684 - 1689
Scavenging of the One-Electron Reduction Product from Nisoldipine with Relevant Thiols: Electrochemical and EPR Spectroscopic Evidences Luis J. Núñez-VergaraG. Díaz-ArayaJ. A. Squella OriginalPaper Pages: 1690 - 1695
Co-Administration of a Water-Soluble Polymer Increases the Usefulness of Cyclodextrins in Solid Oral Dosage Forms Jouko SavolainenKristiina JärvinenTomi Järvinen OriginalPaper Pages: 1696 - 1701
Isothermal and Nonisothermal Decomposition of Thymopentin and Its Analogs in Aqueous Solution Mu-Lan LeeSalomon Stavchansky OriginalPaper Pages: 1702 - 1707
Microencapsulation of Hepatitis B Core Antigen for Vaccine Preparation Takahiro UchidaKouichi ShiosakiKenji Matsuyama OriginalPaper Pages: 1708 - 1713
Quantitative Determination of the Extent of Neutralization of Carboxylic Acid Functionality in Carbopol® 974P NF by Diffuse Reflectance Fourier Transform Infrared Spectrometry Using Kubelka-Munk Function Rong-Hwei JuangDavid E. Storey OriginalPaper Pages: 1714 - 1720
Visualization of PEO-PBLA-Pyrene Polymeric Micelles by Atomic Force Microscopy Jiahorng LiawTakao AoyagiTeruo Okano OriginalPaper Pages: 1721 - 1726
Can the Organization of a Binary Mix Be Predicted from the Surface Energy, Cohesion Parameter and Particle Size of Its Components? J. BarraF. LescureE. Doelker OriginalPaper Pages: 1727 - 1736
Enhanced Encapsulation of Amphotericin B into Liposomes by Complex Formation with Polyethylene Glycol Derivatives Kunikazu MoribeEitaro TanakaMotoharu Iwatsuru OriginalPaper Pages: 1737 - 1742
Ultrasonic Nebulization of Cationic Lipid-Based Gene Delivery Systems for Airway Administration Ravi PillaiKarel PetrakAlain Rolland OriginalPaper Pages: 1743 - 1747
A New Powder Design Method to Improve Inhalation Efficiency of Pranlukast Hydrate Dry Powder Aerosols by Surface Modification with Hydroxypropylmethylcellulose Phthalate Nanospheres Yoshiaki KawashimaTakanori SeriganoHirofumi Takeuchi OriginalPaper Pages: 1748 - 1752
Surface-modified Antiasthmatic Dry Powder Aerosols Inhaled Intratracheally Reduce the Pharmacologically Effective Dose Yoshiaki KawashimaTakanori SeriganoHirofumi Takeuchi OriginalPaper Pages: 1753 - 1759
Antiproliferative and Cytotoxic Effects of Geldanamycin, Cytochalasin E, Suramin and Thiacetazone in Human Prostate Xenograft Tumor Histocultures Yuebo GanJessie L.-S. AuM. Guillaume Wientjes OriginalPaper Pages: 1760 - 1766
Effects of Cholecystokinin Octapeptide on a Pancreatic Acinar Carcinoma in the Rat Amor HajriChristiane Damgé OriginalPaper Pages: 1767 - 1774
Altered Tissue Distribution and Elimination of Amikacin Encapsulated in Unilamellar, Low-Clearance Liposomes (MiKasome®) Robert M. FieldingRamilla O. LewisLotus Moon-McDermott OriginalPaper Pages: 1775 - 1781
Estimation of Oral Bioavailability of a Long Half-Life Drug in Healthy Subjects Amarnath SharmaPeter H. SluggWilliam J. Jusko OriginalPaper Pages: 1782 - 1786
The Relative Bioavailability and In Vivo-In Vitro Correlations for Four Marketed Carbamazepine Tablets Marvin C. MeyerArthur B. StraughnLarry J. Lesko OriginalPaper Pages: 1787 - 1791
Linear Correlation of the Fraction of Oral Dose Absorbed of 64 Drugs Between Humans and Rats Win L. ChiouAbhijit Barve BriefCommunication Pages: 1792 - 1795
Considerations in the Attainment of Steady State: Aggregate vs. Individual Assessment Walter W. HauckThomas N. TozerFrédéric Y. Bois BriefCommunication Pages: 1796 - 1798
Stability of UC-781, in Intestinal Mucosal Homogenates of the Rat, Rabbit, and Pig Guy Van den MooterGeert StasPatrick Augustijns BriefCommunication Pages: 1799 - 1802