Validation of a Decision Support System for Use in Drug Development: Pharmacokinetic Data Serge GuzyAnthony Hunt OriginalPaper Pages: 1287 - 1297
The Determinants of Physician Attitudes and Subjective Norms Toward Drug Information Sources: Modification and Test of the Theory of Reasoned Action Caroline A. GaitherRichard P. BagozziDuane M. Kirking OriginalPaper Pages: 1298 - 1308
Cholera Toxin B-Mediated Targeting of Lipid Vesicles Containing Ganglioside GM1 to Mucosal Epithelial Cells Tianshun LianRodney J. Y. Ho OriginalPaper Pages: 1309 - 1315
Transient Expression of a Purine-Selective Nucleoside Transporter (SPNTint) in a Human Cell Line (HeLa) Marci E. SchanerJuan WangKathleen M. Giacomini OriginalPaper Pages: 1316 - 1321
Iontophoresis of Poly-L-lysines: The Role of Molecular Weight? Norris G. TurnerLaura FerryRichard H. Guy OriginalPaper Pages: 1322 - 1331
The Effect of β-Turn Structure on the Passive Diffusion of Peptides Across Caco-2 Cell Monolayers Gregory T. KnippDavid G. Vander VeldeRonald T. Borchardt OriginalPaper Pages: 1332 - 1340
The Effect of β-Turn Structure on the Permeation of Peptides Across Monolayers of Bovine Brain Microvessel Endothelial Cells Mette SorensenBetina SteenbergRonald T. Borchardt OriginalPaper Pages: 1341 - 1348
Molecular Modeling of Polymers 16. Gaseous Diffusion in Polymers: A Quantitative Structure-Property Relationship (QSPR) Analysis Hitesh C. PatelJohn S. TokarskiA. J. Hopfinger OriginalPaper Pages: 1349 - 1354
Evaluation of Direct Curve Comparison Metrics Applied to Pharmacokinetic Profiles and Relative Bioavailability and Bioequivalence S. A. MarstonJames E. Polli OriginalPaper Pages: 1363 - 1369
Long-Term and High-Temperature Storage of Supercritically-Processed Microparticulate Protein Powders Michael A. WintersPablo G. DebenedettiTodd M. Przybycien OriginalPaper Pages: 1370 - 1378
The Stability of Insulin in Crystalline and Amorphous Solids: Observation of Greater Stability for the Amorphous Form Michael J. PikalDaniel R. Rigsbee OriginalPaper Pages: 1379 - 1387
Interaction of Human IgE with Soluble Forms of IgE High Affinity Receptors Jim LiuJane RuppelSteven J. Shire OriginalPaper Pages: 1388 - 1393
Development and Use of Enzyme-Linked Immunosorbent Assays (ELISA) for the Detection of Protein Aggregates in Interferon-Alpha (IFN-α) Formulations Andrea BraunJochem Alsenz OriginalPaper Pages: 1394 - 1400
Protection Afforded by Maltosyl-β-cyclodextrin Against α-Chymotrypsin-Catalyzed Hydrolysis of a Luteinizing Hormone-Releasing Hormone Agonist, Buserelin Acetate Kazutaka MatsubaraYukihiro AndoKaneto Uekama OriginalPaper Pages: 1401 - 1405
Stabilization of 10-Hydroxycamptothecin in Poly(lactide-co-glycolide) Microsphere Delivery Vehicles Anna ShenderovaThomas G. BurkeSteven P. Schwendeman OriginalPaper Pages: 1406 - 1414
A New Ternary Polymeric Matrix System for Controlled Drug Delivery of Highly Soluble Drugs: I. Diltiazem Hydrochloride Hyunjo KimReza Fassihi OriginalPaper Pages: 1415 - 1421
Characterization of Poly(glycolide-co-D,L-lactide)/Poly(D,L-lactide) Microspheres for Controlled Release of GM-CSF Dean K. PettitJ. Ronald LawterWayne R. Gombotz OriginalPaper Pages: 1422 - 1430
Chitosan and Chitosan/Ethylene Oxide-Propylene Oxide Block Copolymer Nanoparticles as Novel Carriers for Proteins and Vaccines Pilar CalvoCarmen Remuñan-LópezMaría José Alonso OriginalPaper Pages: 1431 - 1436
Effect of Drug Load and Plate Coating on the Particle Size Distribution of a Commercial Albuterol Metered Dose Inhaler (MDI) Determined Using the Andersen and Marple-Miller Cascade Impactors Moheb M. NasrDanna L. RossNicholas C. Miller OriginalPaper Pages: 1437 - 1443
Glucuronidation of Entacapone, Nitecapone, Tolcapone, and Some Other Nitrocatechols by Rat Liver Microsomes Pia LautalaMaija KivimaaJyrki Taskinen OriginalPaper Pages: 1444 - 1448
Biomimetic Metabolism of Artelinic Acid by Chemical Cytochrome P-450 Model Systems Olutosin R. IdowuAi J. LinJames O. Peggins OriginalPaper Pages: 1449 - 1454
The Design and Validation of a Novel Intravenous Microdialysis Probe: Application to Fluconazole Pharmacokinetics in the Freely-Moving Rat Model Hua YangQin WangWilliam F. Elmquist OriginalPaper Pages: 1455 - 1460
The Pharmacokinetics of Topotecan and Its Carboxylate Form Following Separate Intravenous Administration to the Dog Brian E. DaviesElisabeth A. MinthornJos H. Beijnen OriginalPaper Pages: 1461 - 1465
Effects of Low and High Density Lipoproteins on Renal Cyclosporine A and Cyclosporine G Disposition in the Isolated Perfused Rat Kidney Michelle L. StrongClarence T. Ueda OriginalPaper Pages: 1466 - 1471
Protein Aggregates Seem to Play a Key Role Among the Parameters Influencing the Antigenicity of Interferon Alpha (IFN-α) in Normal and Transgenic Mice Andrea BraunLia KweeJochem Alsenz OriginalPaper Pages: 1472 - 1478
Lymphatic Uptake and Biodistribution of Liposomes After Subcutaneous Injection: III. Influence of Surface Modification with Poly(ethyleneglycol) Christien OussorenGert Storm OriginalPaper Pages: 1479 - 1484
Relationship Between Size of Injected Microspheres and Ultrasound Imaging of Heart by PLSR K. DyrstadP. C. Sontum OriginalPaper Pages: 1485 - 1489
A New Approach for Direct In Vivo Dissolution Studies of Poorly Soluble Drugs Lisbet BønløkkeFinn Norring ChristensenHans Lennernäs Note Pages: 1490 - 1492
Burger's Medicinal Chemistry and Drug Discovery. Manfred E. Wolff, Ed. John Wiley & Sons, Inc., One Wiley Drive, Somerset, NJ 08875. ReviewPaper Pages: 1493 - 1498