Abstract
Biomedical porous Ti-15Mo alloys were prepared by microwave sintering using ammonium hydrogen carbonate (NH4HCO3) as the space holder agent to adjust the porosity and mechanical properties. The porous Ti-15Mo alloys are dominated by β-Ti phase with a little α-Ti phase, and the proportion of α and β phase has no significant difference as the NH4HCO3 content increases. The porosities and the average pore sizes of the porous Ti-15Mo alloys increase with increase of the contents of NH4HCO3, while all of the compressive strength, elastic modulus and bending strength decrease. However, the compressive strength, bending strength and the elastic modulus are higher or close to those of natural bone. The surface of the porous Ti-15Mo alloy was further modified by hydrothermal treatment, after which Na2Ti6O13 layers with needle and flake-like clusters were formed on the outer and inner surface of the porous Ti-15Mo alloy. The hydrothermally treated porous Ti-15Mo alloy is completely covered by the Ca-deficient apatite layers after immersed in SBF solution for 14 d, indicating that it possesses high apatiteforming ability and bioactivity. These results demonstrate that the hydrothermally treated microwave sintered porous Ti-15Mo alloys could be a promising candidate as the bone implant.
摘要
本文采用微波烧结制备了生物医用多孔Ti-15Mo合金, 并以碳酸氢铵为造孔剂调节合金孔隙率及力学性能. 多孔Ti-15Mo合金是由主晶相β-Ti和少量α-Ti组成, 其中α/β的比例随碳酸氢铵含量的增加无明显变化. 随着碳酸氢铵含量的增加, 多孔Ti-15Mo合金的孔隙率和孔径均随之增加, 而抗压强度、 弹性模量和抗弯强度随之下降. 然而, 合金的抗压强度、 抗弯强度和弹性模量均高于或接近于自然骨. 采用水热法对多孔Ti-15Mo合金进行表面活化处理后, 多孔Ti-15Mo合金外表面和内表面均形成了针片状的Na2Ti6O13涂层. 水热处理试样经SBF溶液浸泡14天后, 内外表面均完全被缺钙的磷灰石层所覆盖, 说明水热处理的多孔Ti-15Mo合金具有优异的磷灰石形成能力和生物活性. 由此可见, 水热处理的微波烧结多孔Ti-15Mo合金是一种非常有前途的骨植入材料.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China (51101085), the Aeronautical Science Foundation of China (2015ZF56027), the Natural Science Foundation of Jiangxi Province (2016BAB206109), the Science and Technology Support Plan Project of Jiangxi Province (20151BBG70039), and the Science and Technology Project of Jiangxi Province Education Department (GJJ150721).
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Jilin Xu is currently an associate professor at the School of Materials Science and Engineering, Nanchang Hangkong University. He was born in Ningdu, Jiangxi province, China, in 1982. He received his PhD degree in materials physics and chemistry from Harbin Institute of Technology, China, in 2009. His research focuses on the biomedical metallic materials and the corrosion and protection of metals.
Yufeng Zheng received his PhD in materials science from Harbin Institute of Technology, China, in 1998. Since 2004, he has been a full professor at Peking University in Beijing, China. His research focuses on the development of various new biomedical metallic materials (biodegradable Mg, Fe and Zn based alloys, β-Ti alloys with low elastic modulus, bulk metallic glass, ultra-fine grained metallic materials, etc.).
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Xu, J., Zhang, J., Bao, L. et al. Preparation and bioactive surface modification of the microwave sintered porous Ti-15Mo alloys for biomedical application. Sci. China Mater. 61, 545–556 (2018). https://doi.org/10.1007/s40843-017-9098-2
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DOI: https://doi.org/10.1007/s40843-017-9098-2