Abstract
The whole plants of Ypsilandra thibetica have been analyzed as part of a systematic study on saponin constituents of medicinal plants. This has resulted in the isolation of two new bisdesmosidic furostanol saponins, named ypsilandroside P (1) and ypsilandroside Q (2), and one new pregnane glycoside, named ypsilandroside R (3), together with nine known steroidal glycosides. Their structures were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic hydrolysis. Ypsilandroside P (1) was cytotoxicity against two human tumor cell lines.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Hou K. Z. Dictionary of the Families and Genera of Chinese Seed Plants (Second Edition); Science Press: Beijing, 1982; pp 521.
Jiangsu New Medical College. Dictionary of Traditional Chinese Crude Drugs; Shanghai Press of Science and Technology: Shanghai, 1977; pp 1841.
Xie, B. B.; Liu, H. Y.; Ni, W.; Chen, C. X.; Lü, Y.; Wu, L.; Zheng, Q. T. Chem. Biodivers.2006, 3, 1211–1218.
Xie, B. B.; Liu, H. Y.; Ni, W.; Chen, C. X. Steroids2009, 74, 950–955.
Lu, Y.; Chen, C. X.; Ni, W.; Hua, Y.; Liu, H. Y. Steroids2010, 75, 982–987.
Lu, Y.; Xie, B. B.; Chen, C. X.; Ni, W.; Hua, Y.; Liu, H. Y. Helv. Chim. Acta2011, 94, 92–97.
Zhao, Y.; Feng, B.; Kang, L. P.; Li, B.; Huang, H. Z.; Cong, Y. W.; Ma, B. P. Chin. J. Nat. Med.2009, 7, 381–389.
Zhao, Y.; Kang, L. P.; Liu, Y. X.; Liang, Y. G.; Tan, D. W.; Yu, Z. Y.; Cong, Y. W.; Ma, B. P. Planta Med.2009, 75, 356–363.
Nohara, T.; Ito, Y.; Seike, H.; Komori, T.; Moriyama, M.; Gomita, Y.; Kawasaki, T. Chem. Pharm. Bull.1982, 30, 1851–1856.
Hirai, Y.; Sanada, S.; Ida, Y.; Shoji, J. Chem. Pharm. Bull.1986, 34, 82–87.
Chen, C. X.; Zhou, J.; Zhang, Y. T.; Zhao, Y. Y. Acta Bot. Yunnan.1990, 12, 323–329.
Shao, B.; Guo, H.; Cui, Y.; Ye, M.; Han, J.; Guo, D. Phytochemistry2007, 68, 623–630.
Xiao, C. M.; Huang, J.; Zhong, X. M.; Tan, X. Y.; Deng, P. C. Helv. Chim. Acta2009, 92, 2587–2595.
Sautour, M.; Mitaine-Offer, A. C.; Miyamoto, T.; Dongmo, A.; Lacaille-Dubois, M. A. Chem. Pharm. Bull.2004, 52, 1353–1355.
Agrawal, P. K.; Jain, D. C.; Gupta, R. K.; Thakur, R. S. Phytochemistry1985, 24, 2479–2496.
Kiyosawa, S.; Hutoh, M.; Komori, T.; Nohara, T.; Hosokawa, I.; Kawasaki, T. Chem. Pharm. Bull.1968, 16, 1162–1164.
Nohara, T.; Miyahara, K.; Kawasaki, T. Chem. Pharm. Bull.1975, 23, 872–885.
Agrawal, P. K. Magn. Reson. Chem.2004, 42, 990–993.
Agrawal, P. K. Steroids2005, 70, 715–724.
Agrawal, P. K. Phytochemistry1992, 31, 3307–3330.
Kasai, R.; Okihara, M.; Asakawa, J.; Mizutani, K.; Tanaka, O. Tetrahedron1979, 35, 1427–1432.
Mosmman T. J. Immunol. Methods1983, 65, 55–63.
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is published with open access at Springerlink.com
Electronic supplementary material
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Liu, HY., Chen, CX., Lu, Y. et al. Steroidal and pregnane glycosides from Ypsilandra thibetica. Nat. Prod. Bioprospect. 2, 11–15 (2012). https://doi.org/10.1007/s13659-011-0039-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13659-011-0039-z