Abstract
We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of 950 mCi of 131I. On follow-up, her thyroglobulin levels had demonstrated a rising trend (from 3789.0 to 4240.0 ug/L) despite a 123I whole-body scan demonstrating a reduction in tracer avid lesions. She was suspected of having radio-resistant disease. The patient underwent both 18F-FDG and 68Ga-PSMA PET/CT imaging with both scans demonstrating congruent lesions however with far greater intensity on the 68Ga-PSMA study.
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Acknowledgments
We would like to thank the staff of the Department of Nuclear Medicine of Steve Biko Academic Hospital for performing the scans.
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This study was self-funded by the Department of Nuclear Medicine.
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Thabo Lengana, Ismaheel O. Lawal, Kgomotso Mokoala, Mariza Vorster, and Mike M. Sathekge declare that they have no conflict of interest.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Lengana, T., Lawal, I.O., Mokoala, K. et al. 68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?. Nucl Med Mol Imaging 53, 442–445 (2019). https://doi.org/10.1007/s13139-019-00621-x
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DOI: https://doi.org/10.1007/s13139-019-00621-x