Abstract
The formation of glass-ceramics based on Na2O–CaO-silicates containing P2O5 with minor additives of some trivalent oxides (e.g. La, In, Ga, and Al), has been investigated. Different crystalline phases including sodium-orthosilicate containing lanthanum, or aluminum were formed together with Na2Ca2Si3O9, NaInSi2O6, and Na3Ga2Si3O10. The nature and mechanism of HA formed in the glass-ceramics are considered. In general, the presence of trivalent oxides in the glass-ceramics progressively reduced the ability to form a calcium phosphate layer on the surfaces of the materials. The addition of In2O3 decreased the crystallization of the hydroxyapatite layer. However, in the presence of either Ga2O3 or Al2O3 only the amorphous calcium phosphate layer was formed after the immersion of the crystallized specimens in the SBF solution.
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References
Sainz MA, Pena P, Serena S, Caballero A (2010) Influence of design on bioactivity of novel CaSiO3–CaMg(SiO3)2 bioceramics: in vitro simulated body fluid test and thermodynamic simulation. Acta Biomaterial 6:2797–2807
Vitale-Brovarone C, Verné E, Robiglio L, Martinasso G, Canuto RA, Muzio G (2008) Biocompatible glass-ceramic materials for bone substitution. J Mater Sci Mater Med 19:471–478
Chen QZ, Efthymiou A, Salih V, Boccaccini AR (2008) Bioglass-derived glass-ceramic scaffolds: study of cell proliferation and scaffold degradation in vitro. J Biomed Mater Res A 84:1049–1060
Hench LL (2006) The story of bioglass. J Mater Sci Mater Med 17:967–8
Dieudonne SC, Van den Dolder J, de Ruijter JE, Paldan H, Peltola T, Van MA, Hof T, Happonen RP, Jansen JA (2002) Osteoblast differentiation of bone marrow stromal cells cultured on silica gel and sol–gel-derived titania. Biomaterials 23:3041–3051
Arstila H, Vedel E, Hupa L, Hupa M (2007) Factors affecting crystallization of bioactive glasses. J Eur Ceram Soc 27:1543–1546
Karlsson KH, Backman R (2005) In: Pye LD, Montenero A, Joseph I (eds) Properties of glass-forming melts. Taylor & Francis, Boca Raton, FL, p 11
Lin F, Hon M (1988) A study on bioglass ceramics in the Na2O–CaO–SiO2–P2O5 system. J Mat Sci 23:4295–4299
Lahl N, Singh K, Singheiser L, Hilpert K (2000) Crystallization kinetics in AO-AbO3-SiO2-B2O3 glasses. J Mat Sci 35:3089–3096
Schwickest T, Sievering R, Geasee P, Conradt R (2002) Glass ceramic materials as sealants for SOFC applications. Mat-wissu Werkstofftech 33:363–366
Branda F, Arcobello-Varlese F, Costantini A, Luciani G (2002) Effect of the substitution of M2O3 (M=La, Y, In, Ga, Al) for CaO on the bioactivity of 2.5CaO 2SiO2 glass. Biomaterials 23:711–716
Singh K, Bala I, Kumar V (2009) Structural, optical and bioactive properties of calcium borosilicate glasses. Ceram Int 35:3401–3406
Al-Haidary J, Al-Haidari M, Qrunfuleh S (2008) Effect of yttria addition on mechanical, physical and biological properties of bioactive MgO–CaO–SiO2–P2O5–CaF2 glass ceramic. Biomed Mater 3:1500–1505
Kokubo T, Kushitani H, Yamamuro T (1990) Solutions able to reproduce in vivo surface-structure changes in bioactive glass-ceramic A-W. J Biomed Mater Res 24:721–34
McMillan PW (1979) Glass-ceramics. Academic Press, London
Weast RC (1977–1978) CRC handbook of chemistry and physics, 58th ed., CRC, Ohio
Rawson H (1967) Inorganic glass-forming systems. Academic Press, New York
Ray NH (1974) Composition property relationships in inorganic oxide glasses. J Non-Cryst Solids 15:423–434
Branda F, Arcobello-Varlese F, Costantini A, Luciani G (1999) Tg and FTIR of (2.5 - x)CaO.x/3M2O3.2SiO2 (M=Y, La, In, Al, Ga) glasses. J Non-Cryst Solids 246:27–33
Guanabara P (2004) Bioactivity study of glass-ceramics with various crystalline fractions obtained by controlled crystallization. Mat Sci Eng C 24:689–691
Peitl O, Zanotto ED, Hench LL (2001) Highly bioactive P2O5–Na2O–CaO–SiO2 glass–ceramics. J Non-Cryst Solid 292:115–26
Salman SM, Salama SN, Darwish H, Abo-Mosallam HA (2009) In vitro bioactivity of glass–ceramics of the CaMgSi2O6–CaSiO3–Ca5(PO4)3 F–Na2SiO3 system with TiO2 or ZnO additives. Ceram Int 35:1083–1093
Deer WA, Howie RA, Zussman (1992) An introduction to the rock forming minerals. Third ELBS impression. Commonwealth, Printing Press Ltd, Hong Kong
Radovan D, Vera D, Predrag V, Smilja M, Slobodan M (2004) Structural characterization of pure Na-nephelines synthesized by zeolite conversion route. J Phys Chem Solids 65:1623–1633
Balamurugan A, Balossier G, Michel J, Kannan S, Benhayoune H, Rebelo AHS, Ferreira JMF (2007) Sol gel derived SiO2–CaO–MgO–P2O5 bioglass system-preparation and in vitro characterization. J Biomed Mater Res B 83:546–553
Ohtsuki C, Kokubo T, Yamammuro T (1992) Mechanism of apatite formation on CaO–SiO2–P2O5 glasses in a simulated body fluid. J Non-Cryst Solids 143:84–92
Dorozhkin SV, Dorozhkina EI, Epple M (2003) Precipitation of carbonateapatite from a revised simulated body fluid in the presence of glucose. J Appl Biomater Biomech 1:200–2007
Chen QZ, Thompsonb ID, Boccaccinia AR (2006) 45S5 Bioglasss-derived glass–ceramic scaffolds for bone tissue engineering. Biomaterials 27:2414–2425
Peitl O, LaTorre GP, Hench LL (1996) Effect of crystallization on apatite layer formation of bioactive glass 45S5. J Biomed Mater Res 30:509–14
Constantini A, Fresca R, Buri A, Branda F (1997) Effect of the substitution of Y2O3 for CaO on the bioactivity of 2.5CaO·2SiO2 glass. Biomaterials 18:453–458
Singh RK, Srinivasan A (2010) Bioactivity of ferrimagnetic MgO–CaO–SiO2–P2O5–Fe2O3 glass-ceramics. Ceram Int 36:283–290
Ylanen H, Karlsson K, Itala A, Aro HT (2000) Effect of immersion in SBF on porous bioactive bodies made by sintering bioactive glass microspheres. J Non-Cryst Solids 275:107–115
Hench LL, Wilson J (1984) Surface-active biomaterials. Science 226:630–636
Salama SN, Darwish H, Abo-Mosallam HA (2006) HA forming ability of some glass-ceramics of the CaMgSi2O6–Ca5(PO4)3 F–CaAl2SiO6 system. Ceram Int 32:357–364
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The authors would like to thank the National Research Centre, Dokki, Cairo, Egypt for the facilities provided.
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Salman, S.M., Salama, S.N. & Abo-Mosallam, H.A. Crystallization and Ability of Hydroxyapatite Formation in Some Trivalent Oxides Containing Na-Ca-Silicate Glass-Ceramics. Silicon 3, 199–205 (2011). https://doi.org/10.1007/s12633-011-9099-2
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DOI: https://doi.org/10.1007/s12633-011-9099-2