Abstract
A new cell cycle inhibitor, nidurufin (1), was isolated from the marine-derived fungus Penicillium flavidorsum SHK1-27. An evaluation of antitumor activity indicated that 1 induced in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and timedependent manner, with an IC50 value of 12.6 M.
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Ren, H., Liu, Ww. Nidurufin as a new cell cycle inhibitor from marine-derived fungus Penicillium flavidorsum SHK1-27. Arch. Pharm. Res. 34, 901–905 (2011). https://doi.org/10.1007/s12272-011-0606-1
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DOI: https://doi.org/10.1007/s12272-011-0606-1