Abstract
A convenient and useful method for the voltammetric determination of dopamine (DA) and norepinphrine (NE) based on poly(L-aspartic acid) modified glassy carbon electrode (GCE) is reported in this paper. The modified electrode exhibits excellent electro-catalytic activities for the oxidation–reduction of DA and NE, as well as eliminating the interference of ascorbic acid (AA) and uric acid (UA). Factors influencing the detection processes are optimized and the kinetic parameters are calculated. Under the optimal conditions, the anodic peak currents of DA and NE are linear with their concentration and the detection limits (S/N = 3) are 1.0 × 10 − 9 mol L − 1 for DA and 4.31 × 10 − 9 mol L − 1 for NE, respectively. The practical application of this method is demonstrated by determining the concentration of NE and DA in injection which is commercially available with satisfactory results. Compared with other electrochemical methods, this method is simple, highly selective and sensitive.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Gotoh M, Takagi J, Mori S, Yatoh M, Hirooka Y, Yamanouchi K and Smythe G A 2001 Brain Res. 919 155
Kvetnansky R, Noskov V B, Blazicek P, Macho L, Grigoriev A I, Goldstein D S and Kopin I J 1994 Acta Astronaut. 34 243
Hows M E P, Lacroix L, Heidbreder C, Organ A J and Shah A J 2004 J. Neurosci. Methods 138 123
Jung M C, Shi G Y, Borland L, Michael A C and Weber S G 2006 Anal. Chem. 78 1755
Zhu M, Huang X M, Li J and Shen H X 1997 Anal. Chim. Acta 357 261
Whiting M J 2009 Ann. Clin. Biochem. 46 129
Lu L P, Wang S Q and Lin X Q 2004 Anal. Chim. Acta 519 161
Wu H P, Cheng T L and Tseng W L 2007 Langmuir 23 7880
Sun Y, Fei J, Hou J, Zhang Q, Liu Y and Hu B 2009 Microchim. Acta 165 373
Ates M, Castillo J, Sezai Sarac A and Schuhmann W 2008 Microchim. Acta 160 247
Zhang L 2008 Microchim. Acta 161 191
Qing W, Liu X, Lu H, Liang J and Liu K 2008 Microchim. Acta 160 227
Lai G, Zhang H and Han D 2008 Microchim. Acta 160 233
Li Y, Huang X, Chen Y, Wang L and Lin X 2008 Microchim. Acta 164 107
Wang G, Sun J, Zhang W, Jiao S and Fang B 2008 Microchim. Acta 164 357
Chen P Y, Vittal R, Nien P C and Ho K C 2009 Biosens. Bioelectron. 24 3504
Prakash S, Rao C R K and Vijayan M 2009 Electrochim. Acta 54 5919
Wang Y, Li Y M, Tang L H, Lu J and Li J H 2009 Electrochem. Commun. 11 889
Thiagarajan S, Tsai T H and Chen S M 2009 Biosens. Bioelectron. 24 2712
WeiM, Terashima C, FujishimaML A and Gu Z Z 2009 Chem. Commun. 3624
Arguello J, Leidens V L, Magosso H A, Ramos R R and Gushikem Y 2008 Electrochim. Acta 54 560
Abbaspour A and Ghaffarinejad A 2009 Anal. Chem. 81 3660
Bian C, Zeng Q, Xiong H, Zhang X and Wang S 2010 Bioelectrochem. 79 1
Huang S, Liao H and Chen D 2010 Biosens. Bioelectron. 25 2351
Mohammad M, Hadi B, Mohammad A S, Hossein N and Nima T 2010 Appl. Catalys. A 378 195
Zhang L and Lin X 2005 Anal. Bioanal. Chem. 382 1669
Ma W and Sun D M 2007 Acta Phys. Chim. Sin. 23 332
Jiang C, Yang T, Jiao K and Gao H 2008 Electrochim. Acta 53 2917
Wang X L, Yang T, Feng Y Y, Jiao K and Li G C 2009 Electroanalysis 21 819
Laviron E 1979 J. Electroanal. Chem. 101 19
Bard A J and Faulkner L R 2001 Electrochemical methods: Fundamentals and applications (New York: John Wiley and Sons Inc), pp. 97
Bond A M 1980 Modern polarographic methods in analytical chemistry (New York: Marcel Dekker), pp. 27
Chen Q, Ai H, Ma Q and Yin H 2010 J. Appl. Electrochem. 40 1379
Jahan B R, Abolfazl K, Reza O, Roudabeh V and Sahar R 2010 J. Solid State Electrochem. 14 1171
Kim Y, Bong S, Kang Y, Yang Y, Mahajan R K, Kim J S and Kim H 2010 Biosen. Bioelectron. 25 2366
Cao X, Zhang L, Cai W and Li Y 2010 Electrochem. Commun. 12 540
Zhou X, Zheng N, Hou S, Li X and Yuan Z 2010 J. Electroanal. Chem. 642 30
Author information
Authors and Affiliations
Corresponding author
Electronic Supplementary Material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
YU, Z., LI, X., WANG, X. et al. Voltammetric determination of dopamine and norepinphrine on a glassy carbon electrode modified with poly (L-aspartic acid). J Chem Sci 124, 537–544 (2012). https://doi.org/10.1007/s12039-011-0179-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12039-011-0179-z