Opinion statement
Systemic mastocytosis is a rare clinical disorder characterized by the proliferation of mast cells, which are commonly in the skin but may be found in other body sites as well. Mast cells contain chemically active substances that, on release, produce symptoms associated with the disease. The intent of this review is to provide some insight into the clinical nature of this disorder.
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References and Recommended Reading
Pauls J, Brems J, Pockros PJ, et al.: Mastocytosis: diverse presentations and outcomes. Arch Intern Med 1999, 159:401–405. The authors review some of the more unusual manifestations of the disease.
Scolapio JS, Woodward TA: Endoscopic findings in systemic mastocytosis. Gastrointest Endosc 1996, 44:608–610. This article documents with photographs the endoscopic appearance of the disease.
Marone G, Spadaro G, Granata F, Triggiani M: Treatment of mastocytosis: pharmacologic basis and current concept. Leuk Res 2001, 25:583–594. Overall, this review presents a nice overview of the interface between physiology and phamacology in systemic mastocytosis
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Woodward, T. Systemic mastocytosis. Curr Treat Options Gastro 6, 35–38 (2003). https://doi.org/10.1007/s11938-003-0031-8
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DOI: https://doi.org/10.1007/s11938-003-0031-8