Abstract
Liposarcomas are the most common soft tissue sarcomas in adults, although liposarcomas of the chest are uncommon. We report two cases of giant liposarcoma in the mediastinum and chest wall, respectively. An 82-year-old man presented with a mass in the right upper mediastinum, as seen by computed tomography (CT). He had a past history of subcutaneous lipoma resection on his back (19 years previously). The patient underwent tumor resection with a right thoracotomy. A 58-year-old woman presented with an enlarging mass of the right lateral chest, involving the diaphragm and ribs, as seen by CT. She had a past history of subcutaneous lipoma resection of the right chest (18 years previously). The patient underwent an en bloc resection that included the tumor and a part of the right diaphragm and ribs. Histological examination of both patients’ tumors revealed a well-differentiated liposarcoma, with no pathological relation to the previous lipoma resected in either case.
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Schweitzer DL, Aguam AS. Primary liposarcoma of the mediastinum: report of a case and review of the literature. J Thorac Cardiovasc Surg 1977;74:83–97.
Enzinger FM, Weiss SW. Soft tissue tumors. 3rd edn. St. Louis: Mosby; 1995.
Eisenstat R, Bruce D, Williams LE, Katz DS. Primary liposarcoma of the mediastinum with coexistent mediastinal lipomatosis. AJR Am J Roentgenol 2000;174:572–573.
Epler GR, McLoud TC, Munn CS, Colby TV. Pleural lipoma: diagnosis by computed tomography. Chest 1986;90:265–268.
Binh MB, Sastre-Garau X, Guillou L, de Pinieux G, Terrier P, Lagace R, et al. MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data. Am J Surg Pathol 2005;29:1340–1347.
Aubert A, Chaffanjon P, Peoch M, Brichon PY. Chest wall implantation of a mediastinal liposarcoma after thoracoscopy. Ann Thorac Surg 2000;69:1579–1580; discussion 1581.
Inaba H, Furuta Y, Usuda R, Ohta S, Nakajima N, Muro H. Liposarcoma originating in the neck and the mediastinum after removal of mediastinal lipoma. Kyobu Geka 2004;57:935–940. do10.1007/s11748-008-0331-y
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Shoji, T., Sonobe, M., Okubo, K. et al. Giant primary liposarcoma of the chest. Gen Thorac Cardiovasc Surg 57, 159–161 (2009). https://doi.org/10.1007/s11748-008-0329-5
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DOI: https://doi.org/10.1007/s11748-008-0329-5