Abstract
This study was designed to investigate alterations in coagulation, and in biochemical and haematological parameters in cattle with traumatic reticuloperitonitis (TRP). In the study, 28 dairy cattle with TRP and 10 clinically healthy cattle (control) of different ages and breeds were used. Cattle with TRP had prolonged prothrombin time (PT), thrombin time (TT) and activated partial thromboplastin time (APTT). Erythrocytopenia, thrombocytopenia and hyperfibrinogenaemia were detected in animals with TRP. Furthermore, the serum concentrations of total protein, globulin and total bilirubin, and the activities of alkaline phosphatase (ALP) and aspartate aminotransferase (AST) were also high in cattle with TRP compared to those of the control group. The serum concentrations of calcium were significantly low in the TRP group. The results of this study, therefore, indicate that TRP causes significant coagulation abnormalities and biochemical and haematological alterations in dairy cattle.
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Abbreviations
- A/G:
-
albumin globulin ratio
- ALP:
-
alkaline phosphatase
- APTT:
-
activated partial thromboplastin time
- AST:
-
aspartate aminotransferase
- AT-III:
-
antithrombin III
- Ca:
-
calcium
- FDPs:
-
fibrinogen degradation products
- GCT:
-
glutaraldehyde coagulation test
- Hb:
-
haemoglobin concentration
- P:
-
phosphorus
- PCV:
-
packed cell volume
- PT:
-
prothrombin time
- RBCs:
-
total red blood cells
- TRP:
-
traumatic reticuloperitonitis
- TT:
-
thrombin time
- WBCs:
-
total white blood cells
References
Aiello, S.E., 1998. Traumatic reticuloperitonitis, hemostatic disorders, haematologic reference ranges. In: S.E. Aiello (ed.), The Veterinary Merck Manual, 8th edn, (Merck, Pennsylvania), 188–190, 39–48, 2190
Barton, M.H., Morris, D.D., Norton, N. and Passé, K.W., 1998. Hemostatic and fibrinolytic indices in neonatal foals with presumed septicemia. Journal of Veterinary Internal Medicine, 12, 26–35
Carey, M. and Rodgers, G.M., 1998. Disseminated intravascular coagulation: clinical and laboratory aspects. American Journal of Hematology, 59, 65–73
Coles, E.H., 1986. Erythrocytes, leukocytes, hemostasis and coagulation of blood. In: E.H. Coles (ed.), Veterinary Clinical Pathology, 4th edn, (W.B. Saunders, Philadelphia), 12–22, 48–56, 98–1113
Dodds, W.J., 1997. Hemostasis. In: J.J. Kaneko; J.W. Harvey and M.L. Bruss (eds), Clinical Biochemistry of Domestic Animals, 5th edn, (Academic Press, San Diego), 241–283
Fubini, S.L., Yeager, A.E., Mohammed, H.O. and Smith, D.F., 1990. Accuracy of radiography of the reticulum for predicting surgical findings in adult dairy cattle with traumatic peritonitis: 123 cases (1981–1987). Journal of the American Veterinary Medical Association, 197, 1060–1064
Hirvonen, J. and Pyorala, S., 1998. Acute-phase response in dairy cattle with surgically-treated abdominal disorders. Veterinary Journal, 55, 53–61
Imren, H.Y., 1982. Studies on the alterations of blood and urine Ca and P in cattle with traumatic reticuloperitonitis [in Turkish]. Journal of Faculty Veterinary Medicine, University of Ankara, 29, 71–78
Jafarzadeh, S.R., Nowrouzian, I., Khaki, Z., Ghamsari, S.M. and Adibhashemi, F., 2004. The sensitivities of total plasma protein and plasma fibrinogen for the diagnosis of traumatic reticuloperitonitis in cattle. Preventive Veterinary Medicine, 65, 1–7
Kramer, J.W. and Hoffmann, W.E., 1997. Clinical enzymology. In: J.J. Kaneko; J.W. Harvey and M.L. Bruss (eds), Clinical Biochemistry of Domestic Animals, 5th edn, (Academic Press, San Diego), 315–317
Levi, M., de Jonge, E. and van der Poll, T., 2001. Rationale for restoration of physiological anticoagulant pathways in patients with sepsis and disseminated intravascular coagulation. Critical Care Medicine, 29, 90–94
Liberg, P., 1981. Glutaraldehyde and formol-gel tests in bovine traumatic peritonitis. Acta Veterinaria Scandinavica, 22, 78–84
Lisciandro, S.C, Hohenhaus, A. and Brooks, M., 1998. Coagulation abnormalities in 22 cats with naturally occurring liver disease. Journal of Veterinary Internal Medicine, 12, 71–75
Matsuda, T., 1996. Clinical aspects of DIC—disseminated intravascular coagulation. Polish Journal of Pharmacology, 48, 73–75
Moore, F., 1997. Interpreting serum chemistry profiles in dairy cows. Veterinary Medicine, 92, 903–912
Penner, J.A., 1998. Disseminated intravascular coagulation in patients with multiple organ failure of non-septic origin. Seminars in Thrombosis and Hemostasis, 24, 45–52
Pusterla, N., Braun, U., Forrer, R. and Lutz, H., 1997. Antithrombin-III activity in plasma of healthy and sick cattle. The Veterinary Record, 140, 17–18
Radostits, O.M, Blood, D.C. and Gay, C.C., 1994. Traumatic reticuloperitonitis. In: O.M. Radostits, D.C. Blood, C.C. Gay (eds), Veterinary Medicine: A Textbook of the Diseases of Cattle, Sheep, Pigs, Goats and Horses, 8th edn, (W.B. Saunders, London), 278–284
Roth, L. and King, J.M., 1991. Traumatic reticulitis in cattle: a review of 60 fatal cases. Journal of Veterinary Diagnostic Investigations, 3, 52–54
Roussel, A.J, Whitney, M.S. and Cole, D., 1997. Interpreting a bovine serum chemistry profile: Part 1. Veterinary Medicine, 92, 551–558
Rucker, R.B. and Morris, J.G., 1997. Vitamins. In: J.J. Kaneko; J.W. Harvey and M.L. Bruss (eds), Clinical Biochemistry of Domestic Animals, 5th edn, (Academic Press, San Diego), 716–718
Samad, A., Awaz, K.B. and Sarkate, L.B., 1994. Diagnosis of bovine traumatic peritonitis I: strength of clinical signs in predicting correct diagnosis. Journal of Applied Animal Research, 6, 13–18
Slappendel, R.J., 1988. Disseminated intravascular coagulation. The Veterinary Clinics of North America: Small Animal Practice, 18, 169–183
Ward, J.L. and Ducharme, N.G., 1994. Traumatic reticoluperitonitis in dairy cattle. Journal of the American Veterinary Medical Association, 204, 874–877
Weiss, R.C., Dodds, W.J. and Scott, F.W., 1980. Disseminated intravascular coagulation in experimentally induced feline infectious peritonitis. American Journal of Veterinary Research, 41, 663–671
Weiss, D.J. and Rashid, J., 1998. The sepsis—coagulant axis: a review. Journal of Veterinary Internal Medicine, 12, 317–324
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Gokce, H.I., Gokce, G. & Cihan, M. Alterations in Coagulation Profiles and Biochemical and Haematological Parameters in Cattle with Traumatic Reticuloperitonitis. Vet Res Commun 31, 529–537 (2007). https://doi.org/10.1007/s11259-007-3527-1
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DOI: https://doi.org/10.1007/s11259-007-3527-1