Abstract
Mixed ligand complexes [M(2-AP)(Ala)Cl x · mH2O]nH2O, where (M = CoII, NiII, CrIII and FeIII, 2-AP = 2-acetylpyridine, Ala = alanine, x = 2–3, m = 0–1 and n = 3–5] are synthesized and characterized by elemental analysis, FTIR, UV/Vis., MS, TG, measurements and semi-empirical calculations ZINDO/1 and PM3. The results suggest an octahedral geometry for all isolated complexes. FTIR spectra show that alanine coordinates to the metal ions as a neutral unidentate through the amino nitrogen where 2-acetylpyridine coordinates to the metal ion in a bidentate manner through carbonyl oxygen and pyridyl nitrogen. Semi-empirical calculations have been used to study the molecular geometry and the harmonic vibrational spectra with the purpose to assist the experimental assignment of the complexes. The Fe complex showed significant activity as a catalase-like model.
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A. Pasini L.J. Casella (1979) Inorg. Nucl. Chem. 36 2133 Occurrence Handle10.1016/0022-1902(74)80739-6
C.R. Bhattacharjee P.K. Choudhury (2001) Transition Met. Chem. 26 730 Occurrence Handle10.1023/A:1012210617378 Occurrence Handle1:CAS:528:DC%2BD3MXosV2iu7g%3D
L. Wang J. Cai Z.W. Mao X.L. Feng J.W. Huang (2004) Transition Met. Chem. 29 411 Occurrence Handle10.1023/B:TMCH.0000027461.08056.31 Occurrence Handle1:CAS:528:DC%2BD2cXjvVKns7c%3D
M.M. Shoukry E.M. Khairy A.A. El-Sherif (2002) Transition Met. Chem. 27 656 Occurrence Handle10.1023/A:1019831618658 Occurrence Handle1:CAS:528:DC%2BD38Xmt1ymsL0%3D
N. Grosser S. Oberle G. Berndt K. Erdmannk A. Hemmerle (2004) Biochem. Biophys. Res. Commun. 314 351 Occurrence Handle10.1016/j.bbrc.2003.12.089 Occurrence Handle1:CAS:528:DC%2BD2cXltFyntg%3D%3D
D.E. Metzler (1957) J. Am. Chem. Soc. 79 485 Occurrence Handle10.1021/ja01559a068 Occurrence Handle1:CAS:528:DyaG2sXjtVagug%3D%3D
W. Kaim and B. Schwederski, Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, an Introduction and Guide, John Wiley & Sons, 1994
R. Cammack (1988) Adv. Inorg. Chem. Radiochem. 32 297 Occurrence Handle1:CAS:528:DyaL1cXlt1Cksbo%3D Occurrence Handle10.1016/S0898-8838(08)60234-2
D.E. Metzler (1957) J. Am. Chem. Soc. 79 485 Occurrence Handle10.1021/ja01559a068 Occurrence Handle1:CAS:528:DyaG2sXjtVagug%3D%3D
N.A. Nawar A.M. Shallaby N.M. Hosny M.M. Mostafa (2001) Transition Met. Chem. 26 180 Occurrence Handle10.1023/A:1007172905500 Occurrence Handle1:CAS:528:DC%2BD3MXht1Sls70%3D
T. Shoeib C.F. Rodriquez K.W.M. Siu A.C. Hopkinson (2001) Phys. Chem. Chem. Phys. 3 853 Occurrence Handle10.1039/b008836f Occurrence Handle1:CAS:528:DC%2BD3MXhtFyrtL0%3D
P. Comba R. Remenyi (2003) Coord. Chem. Rev. 9 238
A. R. Leach, Molecular Modeling, Longman Edinburgh,1996
A.K. Rappe C.J. Casewit (1997) Molecular Mechanics across Chemistry University Science Books Sausalito
J. Zupan J. Gasteiger (1993) Neural Networks for Chemists: an Introduction VCH Verlag New York, Weinheim
E. Stadtman P. Berlett P. Chock (1990) Proc. Natl. Acad. Sci. U.S.A. 87 384 Occurrence Handle10.1073/pnas.87.1.384 Occurrence Handle1:CAS:528:DyaK3cXnt1ymtg%3D%3D
B. Halliwell J. Gutteridge (1990) Methods in Enzymology Academic Press San Diego
V. Daier H. Biava C. Palopoki S. Shova J. Tuchagues S. Signorella (2004) J. Inorg. Biochem 98 1806 Occurrence Handle10.1016/j.jinorgbio.2004.08.007 Occurrence Handle1:CAS:528:DC%2BD2cXptlOkt7g%3D
J. Gao S.H. Zhong (2000) J. Mol. Cat. A: Chem. 186 25 Occurrence Handle10.1016/S1381-1169(02)00081-X
L. Jose V.N.R. Pillai (1998) Polymer 39 231 Occurrence Handle10.1016/S0032-3861(97)00038-4
Hyperchem 7, developed by Hypercube Inc. 2002
W.J. Geary (1971) Coord. Chem. Rev. 7 81 Occurrence Handle10.1016/S0010-8545(00)80009-0 Occurrence Handle1:CAS:528:DyaE3MXlsVCgsrg%3D
K. Nakamoto (1970) Infrared Spectra of Inorganic and Coordination Compounds John Wiley New York
S.K. Sahni S.K. Sangal S.P. Gupta V.B. Rana (1977) J. Inorg. Nucl. Chem. 39 1098 Occurrence Handle10.1016/0022-1902(77)80280-7 Occurrence Handle1:CAS:528:DyaE2sXmtFSgurY%3D
J.R. Ferraro (1971) Low Frequency Vibrations of Inorganic and Coordination Compounds Plenum press New York
A.B.P. Lever (1986) Inorganic Electronic Spectroscopy Elsevier Amsterdam
F.A. Cotton and G. Wilkinson, Advanced Inorganic Chemistry (A Comprehensive Text), 4th edit., John Wiley, New York, 1980
S. Cakir E. Coskun P. Naumov E. Bicer (2001) J. Mol. Struc. 608 101 Occurrence Handle10.1016/S0022-2860(01)00939-5
A.W. Coats J.P. Redfern (1964) Nature 20 68 Occurrence Handle10.1038/201068a0
D. Kong J. Reibenspies A. Clearfield A.E. Martell (2004) Inorg. Chem. Commun. 7 195 Occurrence Handle10.1016/j.inoche.2003.05.001 Occurrence Handle1:CAS:528:DC%2BD2cXoslChtQ%3D%3D
W.H. Chen H.H. Wei G.H. Lee Y. Wang (2001) Polyhedron 20 515 Occurrence Handle10.1016/S0277-5387(00)00656-2 Occurrence Handle1:CAS:528:DC%2BD3MXitFyktrY%3D
A.G. Raso J.J. Fiol B. Adrover P. Tauler A. Pons I. Mata E.E. Spinosa E. Molins (2003) Polyhedron 22 3255 Occurrence Handle10.1016/S0277-5387(02)01364-5
J. Gao A.E. Martell J.H. Reibenspies (2003) J. Inorg. Chim. Acta 346 23
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Hosny, N.M. Synthesis, characterization, theoretical calculations and catalase-like activity of mixed ligand complexes derived from alanine and 2-acetylpyridine. Transition Met Chem 32, 117–124 (2007). https://doi.org/10.1007/s11243-006-0132-z
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DOI: https://doi.org/10.1007/s11243-006-0132-z