Abstract
A method for the synthesis of promising nitric oxide donors in living organisms, 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides] was elaborated. The method involved replacement of hydroxy groups of the corresponding 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-hydroxyethyl)triaz-1-ene 2-oxides] by halogen atoms and, in some cases, the exchange of one halogen atom for another.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1234—1239, July, 2017.
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Pokhvisneva, G.V., Ternikova, T.V., Smirnov, G.A. et al. Synthesis of 1,1´-[methylenebis(oxy)]bis[3-alkyl-3-(2-haloethyl)triaz-1-ene 2-oxides]. Russ Chem Bull 66, 1234–1239 (2017). https://doi.org/10.1007/s11172-017-1878-5
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DOI: https://doi.org/10.1007/s11172-017-1878-5