Abstract
A convenient method for the synthesis of earlier unknown substituted derivatives of 4-aryl-7-methyl-4,6-dihydro-3H-pyrano[3,2-c]pyridine-2,5-dione and ethyl 3-(4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)-3-arylpropionate was developed based on the multi-component condensation of 4-hydroxy-6-methyl-1H-pyridin-2-one, Meldrum’s acid, and carbonyl compounds.
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On the occasion of the 80th anniversary of the N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 0457–0461, February, 2014.
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Lichitskii, B.V., Osipov, A.O., Komogortsev, A.N. et al. Multi-component condensation of 4-hydroxy-6-methyl-1H-pyridin-2-one with carbonyl compounds and Meldrum’s acid. Russ Chem Bull 63, 457–461 (2014). https://doi.org/10.1007/s11172-014-0452-7
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DOI: https://doi.org/10.1007/s11172-014-0452-7