Abstract
New 3-(4-hydroxybenzyl)piperazine-2,5-dione, together with the known N-[2-(4-hydroxy-phenyl)ethyl]acetamide (N-acetyltyramine), was isolated for the first time from the marine actinobacterium Streptomyces sp. The chemical structures of these compounds were determined by NMR spectroscopy and mass spectrometry. The cytotoxic activities of the compounds were estimated from their effects on sperm and eggs of the sea urchin Strongylocentrotus intermedius.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 807–809, April, 2007.
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Sobolevskaya, M.P., Denisenko, V.A., Moiseenko, A.S. et al. Bioactive metabolites of the marine actinobacterium Streptomyces sp. KMM 7210. Russ Chem Bull 56, 838–840 (2007). https://doi.org/10.1007/s11172-007-0126-9
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DOI: https://doi.org/10.1007/s11172-007-0126-9