A diclofenac-selective electrode with a plasticized polyvinylchloride membrane was developed. The electrode contained an ionic associate of diclofenac with neutral red and its response was linear over the diclofenac concentration range 5 × 10–5 to 5 × 10–2 M with an electrode function slope of (30.0 ± 1.1) - (44.0 ± 1.2) mV/pC. This membrane electrode was used as a sensor for assaying diclofenac in pharmaceutical formulations.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Ukrainian State Pharmacopeia [in Russian], State Scientific Expert Pharmacopeia Center, Khar’kov (2004).
Compendium 2003 - Medicines [in Russian], V. N. Kovalenko and A. P. Viktorov (Eds.), MORION, Kiev (2003).
M. Tubino and R. L. Souza, J. AOAC Int., 88(60), 1684 – 1687 (2005).
A. Arcelloni, R. Lanzi, S. Pedercini, et al., J. Chromatogr. B., 763, 195 – 200 (2001).
R. Rośkar and v. kmetec, J. Chromatogr. B., 788, 57 – 64 (2003).
C. S. P. Sastry, A. S. R. Prasat Tipirneni, and M. V. Suryanarayana, Analyst, 114, 513 – 515 (1989).
A. A. Matin, M. A. Farajzadeh, and A. Joyuban, Il Farmaco, 60, 855 – 858 (2005).
A. Agatonović-Kuštrin, Lj. Živanović M. Zešević, et al., J. Pharm. Biomed. Anal., 16, 147 – 158 (1997).
J. C. Botello and G. P. Caballero, Talanta, 42(1), 105 – 108 (1995).
R. L. Souza and M. Tubino, J. Brazil Chem. Soc., 16(5), 1068 – 1073 (2005).
Zh. O. Kormosh, I. P. Hunka, Ya. R. Bazel, Met. Ob”ekty Khim. Anal., 2(1), 76 – 81 (2007).; http://www.achem.univ.kiev.ua/moca/3/9.htm.
J. A. Arancibia, M. A. Boldrini, G. M. Escandar, Talanta, 52, 261 – 268 (2000).
P. C. Damiani, M. Bearzotti, M. A. Cabezón, et al., J. Pharm. Biomed. Anal., 20, 587 – 590 (1999).
N. M. Kousy, J. Pharm. Biomed. Anal., 20, 185 – 194 (1999).
L. A. Carreira, M. Rizk, Y. El-Shabrawy, et al., J. Pharm. Biomed. Anal., 13, 1331 – 1337 (1995).
S. S. M. Hassan, W. H. Mahmoud, M. A. F. Elmosallany, et al., J. Pharm. Biomed. Anal., 39, 315 – 321 (2005).
M. Shamsipur, F. Jalali, and S. Ershad, J. Pharm. Biomed. Anal., 37, 943 – 947 (2005).
A. O. Santini, H. R. Pezza, and L. Pezza, Talanta, 68, 636 – 642 (2006).
Zh. Kormosh, I. Hunka, Ya. Bazel, et al., CEJC, 5(3), 813 – 823 (2007).
K. Cammann, Working with Ion-Selective Electrodes [Russian translation], Mir, Moscow (1972).
Author information
Authors and Affiliations
Additional information
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 43, No. 7, pp. 54 – 56, July, 2009.
Rights and permissions
About this article
Cite this article
Kormosh, Z.A., Hunka, I.P. & Bazel, Y.R. An ion-selective sensor for assay of diclofenac in medicines. Pharm Chem J 43, 428–430 (2009). https://doi.org/10.1007/s11094-009-0311-2
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11094-009-0311-2