Abstract
The reaction of alkyl isocyanides with dimethyl 1,3-acetonedicarboxylate in the presence of dialkyl acetylenedicarboxylates in CH2Cl2 at ambient temperature leads to highly functionalized 2-amino-4H-pyrans and 1,2-dialkyl 4,6-dimethyl-(1E, 3E)-3 (alkylamino)-5-oxo-1,3-hexadiene-1,2,4,6-tetracarboxylates.
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Nasiri, F., Nazem, F. & Pourdavaie, K. Chemo- and stereoselective reaction between alkyl isocyanides and dimethyl 1,3-acetonedicarbocxylate in the presence of acetylenic esters. Mol Divers 11, 101–105 (2007). https://doi.org/10.1007/s11030-007-9064-6
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DOI: https://doi.org/10.1007/s11030-007-9064-6