Abstract
In this work, a kind of aliphatic biodegradable polyesteramide (PEA) copolymer based on 6-aminocaproic acid, adipic acid, and 1,6-hexane diol was synthesized by melt polycondensation method, and was characterized by 1H-NMR, FTIR and DSC. The PEA fiber was prepared by melt-spinning method. Tensile properties of the as-spun and hot-drawn fibers were also investigated. Hydrolytic degradation behavior of PEA copolymer chips and fibers were evaluated by weight loss in PBS solution with different pH value. The alkaline degradation behavior of fiber was also studied on change of diameter and surface morphology. During alkaline degradation, the PEA fiber underwent surface erosion.
Article PDF
Similar content being viewed by others
Explore related subjects
Discover the latest articles, news and stories from top researchers in related subjects.Avoid common mistakes on your manuscript.
References
I. Arvanitoyannis, A. Nakayama, N. Kawasaki and N. Yamamoto, Synthesis and properties of biodegradable copolyesteramides: nylon 6,6/ɛ-caprolactone copolymers, 1. Angew. Makromol. Chem., 222, 111–123 (1994).
Y. Tokiwa, T. Suzuki and T. Ando, Synthesis of copolyamide-esters and some aspects involved in their hydrolysis by lipase. J. Appl. Polym. Sci., 24, 1701–1711 (1979).
I. Goodman and R. N. Vachon, Copolyesteramides-II, anionic copolymers of caprolactam with caprolactone: preparation and general properties. Eur. Polym. J., 20, 529–537 (1984).
I. Goodman and R. N. Vachon, Copolyesteramides-III, anionic copolymers of caprolactam with caprolactone: crystalline character and mechanical properties. Eur. Polym. J., 20, 539–547 (1984).
I. Goodman, Copolyesteramides-IV, anionic copolymers of caprolactam with caprolactone: molecular and chain structure. Eur. Polym. J., 20, 549–557 (1984).
J. Tuominen and J. V. Seppala, Synthesis and characterization of lactic acid based poly(ester-amide). Macromolecules, 33, 3530–3535 (2000).
X. B. Liu, J. H. Zhang, D. J. Yang, Y. He and F. H. Zhu, Synthesis and characterization of biodegradable polyesteramides containing ɛ-caprolactone segments. Chin. J. Synth. Chem., 7, 109–111 (1999) (in Chinese).
Z. Y. Qian, S. Li, H. L. Zhang and X. B. Liu, Synthesis, characterization and in vitro degradation of biodegradable polyesteramide based on lactic acid. Colloid Polym. Sci., 281, 869–875 (2003).
Z. Y. Qian, S. Li, C. Li and X. B. Liu, Synthesis, characterization and hydrolytic degradation of aliphatic poly(ester-amide) copolymers. Polym. Mater. Sci. Eng., 19, 123–125 (2003) (in Chinese).
Z. Y. Qian, S. Li, C. Li and X. B. Liu, Synthesis and thermal degradation of biodegradable polyesteramide based on ɛ-caprolactone and 11-aminoundecanoic acid. Polym. Degrad. Stab., 81, 279–286 (2003).
M. S. Nikolic and J. Djonlagic, Synthesis and characterization of biodegradable poly(butylene succinate-co-butylene adipate)s. Polym. Degrad. Stab., 74, 263–270 (2001).
Y. He, Z. Y. Qian and X. B. Liu, Alkaline degradation behavior of polyesteramide fibers: surface erosion. Colloid Polym. Sci., 282, 972–978 (2004).
Z. Y. Qian, Y. He, Y. B. Zou, S. Li and X. B. Liu, Structure and property study of degradable polyesteramide fibers: processing and alkaline degradation behaviour. Polym. Degrad. Stab., 83, 127–132 (2004).
C. B. Liu, Y. C. Gu, Z. Y. Qian, L. Y. Fan, J. Li, G. T. Chao, M. J. Tu and W. J. Jia, Hydrolytic degradation behavior of biodegradable polyetheresteramide-based polyurethane copolymers. J. Biomed. Mater. Res. (A), 75(A), 465–471 (2005).
Z. Y. Qian, S. Li, Y. He, H. L. Zhang and X. B. Liu, Hydrolytic degradation study of biodegradable polyesteramide copolymers based on ɛ-caprolactone and 11-aminoundecanoic acid. Biomaterials, 25, 1975–1981 (2004).
Z. Y. Qian, S. Li, H. L. Zhang and X. B. Liu, Synthesis, characterization and in vitro degradation of biodegradable polyesteramide based on lactic acid. Colloid Polym. Sci., 281, 869–875 (2003).
F. Burkersroda, L. Schedl and A. Göpferich, Why degradable polymers undergo surface erosion or bulk erosion? Biomaterials, 23, 4221–4231 (2002).
X. Y. Yuan, F. T. Arthur and K. D. Mak Yao, Surface degradation of poly(L-lactic acid) fibres in a concentrated alkaline solution. Polym. Degrad. Stab., 79, 45–52 (2003).
Author information
Authors and Affiliations
Corresponding author
Additional information
This work was financially supported by Chinese Key Basic Research Program (2004CB518800 and 2004CB518807), and Sichuan Key Project of Science and Technology (06(05SG022-021-02)).
Rights and permissions
About this article
Cite this article
Liu, C., Jia, W., Qian, Z. et al. In Vitro Degradation Behavior of Polyesteramide Copolymer Fiber Based on 6-Aminocaproic Acid, Adipic Acid, and 1,6-Hexane Diol. J Polym Res 14, 31–37 (2007). https://doi.org/10.1007/s10965-006-9077-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10965-006-9077-3