Abstract
Because detrimental effects of exposure to lead (Pb) on human health have been observed, we previously investigated concentrations of Pb in water supplies and blood of adult residents of Riyadh, Saudi Arabia. The objectives of the present study were to: (1) examine seasonal rates of deposition of Pb in dust in several areas of Riyadh city, (2) measure concentrations of Pb in both outdoor and indoor dust, (3) compare concentrations of Pb in dust in Riyadh with those reported for other cities, and (4) quantify Pb in blood of children living in Riyadh. Mean, monthly deposition of PB in outdoor dust was 4.7 × 101 ± 3.6 tons km−2, with a mean Pb concentration of 2.4 × 102 ± 4.4 × 101 μg/g. Mean, monthly deposition of Pb in indoor dust was 2.7 ± 0.70 tons km−2, with a mean concentration of 2.9 × 101 ± 1.5 × 101 μg Pb/g. There was a significant (P < 0.01) correlation between concentrations of Pb in outdoor and indoor dust. There was no correlation between concentrations of Pb in indoor dust and that in blood of children of Riyadh, whereas there was a weakly significant (P < 0.05) correlation between concentrations of Pb in outdoor dust and that in blood of children. The mean (±SD) concentration of Pb in blood of children in Riyadh was 5.2 ± 1.7, with a range of 1.7–1.6 × 101 μg/dl. Concentrations of Pb in blood of 17.8 % of children in Riyadh were greater than 10 μg/dl, which is the CDC’s level of concern.
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Introduction
Concentrations of lead (Pb) in urban areas of the Kingdom of Saudi Arabia (KSA), particularly in Riyadh, and its potential effects on health are of concern (El-Shobokshy et al. 1990; Ahmed and Ishiga 2006; Al-Othman 2010; Aburas et al. 2011; Al-Othman et al. 2012). The principal source of Pb has been attributed to motor vehicle traffic, which are associated with releases of Pb into the adjacent commercial and residential areas (Ewen et al. 2009). Pb is one of the most widely dispersed toxic substances and can cause significant toxicity to people exposed via inhalation, ingestion, or dermal contact (USEPA 1994; Al-Othman 2010; Mielke et al. 2011; Soto-Jimènez and Flegal 2011; Latif et al. 2011; Al-Othman et al. 2012; Ali and Al-Qahtani 2012). Behaviors of children, such as playing outdoors and hand-to-mouth contact, contribute to exposure to Pb, while absorption from the gastrointestinal tract and greater sensitivity to the hazardous effects of Pb making them more susceptible. Hence, Pb is a special hazard for young children (Laidlaw and Taylor 2011). Dust is a pathway of exposure to Pb and in particular for children (Laidlaw et al. 2005; Laidlaw and Taylor 2011). Dust, defined as a solid matter composed of natural biogenic materials, soil, and anthropogenic metallic constituents (Abdul Wahab et al. 2012), can be classified as indoor, such as that in households and schools, or outdoor, such as that in streets, motorways, playgrounds. Indoor and outdoor dust has been investigated as potential sources of exposure of people to metals, including Pb (Yaghi and Abdul-Wahab 2004). The fact that most people spend 80–90 % of their time indoor results in a growing public concern about the quality of indoor air including metals such as Pb (Klepeis et al. 2001; Sharpe 2004).
Despite significant progress in minimizing concentrations of Pb in the environment over the last three decades, Pb is classified second, after only arsenic, on the priority list of hazardous substances, by the Agency for Toxic Substances and Disease Registry (ATSDR, http://www.atsdr.cdc.gov/cercla/) (ATSDR 2011). According to the World Health Organization (WHO), leaded gasoline and emissions from smelters and battery recycling industries constitute the most important major sources of Pb exposure (WHO 2002). In Saudi Arabia, leaded gasoline is a primary source of Pb in soils and dust (El-Shobokshy 1984; El-Shobokshy et al. 1990; Ahmed et al. 1993; Aburas et al. 2011). While the use of leaded gasoline in KSA was phased out in 2001, there is still residual Pb in dust due to historical uses and there is also Pb released in unleaded gasoline. Total fuel consumption of the Saudi industrial sector in 2008 was about 3 million tons of diesel fuel and 8.5 million tons heavy fuel oil (IEA 2010). Accumulation of soil Pb created by leaded gasoline is proportional to highway traffic flow (Mielke et al. 2011). While exposure of children to Pb in dust and paint was first identified more than a century ago (Gibson 1904), the concentrations of Pb in outdoor and indoor dust that are hazardously remain poorly defined.
Previously, concentrations of Pb in water supplies and correlation with those in whole blood of the population of Riyadh were investigated (Al-Othman et al. 2012). That study indicated that concentrations of Pb in blood of a portion of the population of adults exceeded guidelines set by WHO for protection of heath of humans. While water could be the source of some of the Pb observed in blood, it could not explain all of the exposure. Therefore, objectives of the present study were to: (1) quantify Pb in both outdoor and indoor dust, (2) determine monthly rates of deposition of Pb in outdoor and indoor dust in several regions of Riyadh city, (3) compare concentrations of Pb in dust form Riyadh with those of other cities, and (4) quantify Pb in blood of children living in Riyadh and investigate associations with concentrations of Pb in outdoor and indoor dust.
Materials and methods
Chemicals
Unless otherwise stated, all solvents and chemicals were analytical reagent grade (Merck, Darmstadt, Germany). Nitric acid (AnalaR, BDH Laboratory Supplies), hydrochloric acid (Extra pure, Merck, Darmstadt, Germany), hydrofluoric acid (Extra pure, Merck, Darmstadt, Germany) were used during sample preparation and digestion. All water used during sample preparation and atomic absorption spectroscopic analysis was MilliQ water (Millipore S.A., Cedex, Molsheim, France).
Sampling locations
This study was conducted in Riyadh, the largest city and capital of the Kingdom of Saudi Arabia (KSA). The city, which is situated in the center of the Arabian Peninsula, has an area of more than 1,000 km2, is divided into 15 municipalities. Riyadh has a population estimated to be approximately 5.8 million (Saudi CDSI 2007; http://www.cdsi.gov.sa/english/) comprised of 68 % Saudi nationals and 32 % non-Saudis (http://www.cdsi.gov.sa/english/). Samples of dust were collected from three areas: (1) Northern, King Saud University, (2) Central, Al-Olaya, and (3) Southern, Al-Manfouha (Densely populated area) (Fig. 1). Each area was characterized by different activities and environmental features.
Collection of dust and extraction of Pb
Aerosol dust deposition samples of both indoor and outdoor dusts were by use of a MDCO dust collector according to previously published methods (Sow et al. 2006). The MDCO collector consists of a rectangular plastic tray, 52.5 (L) × 31.5 (W) and 10.0 (H) cm, with a flat marble filter fitted on top, which acts as a trap for dust and prevents settled particles from being re-suspended. The amount of dust collected at each location was calculated and expressed as metric tons km−2 by dividing the total weight of the collected sample by the area of the sampler’s opening. Indoor dust was collected from the dust bag of a domestic vacuum cleaner used in respective households to clean carpets and furniture. Samples were air-dried overnight to remove moisture, powdered in an agate mortar, sieved to size <0.2 mm of aperture size with the aid of a stainless steel sieve, and stored in polyethylene bottle for further analysis. Particles greater than 2 mm were removed from samples of dust. Lead was extracted from 0.25 g of each sample of dust by use of a mixture of HNO3:HCl:HF (9:3:2, v/v) acids in a Teflon® beaker and heating in a microwave oven at 150 °C for 10 min. Subsequently, total suspended particulates in the extraction residue were dissolved in 25 ml of 20 % HNO3 and rewarmed to 80 °C for 20 min. The solution was made up to 50 ml with MilliQ® water after filtration.
Collection and preparation of blood
The study population consisted of 300 healthy male school children whose ages ranged from 6 to 14 yr. The legal guardian for each child signed a consent form that authorized the collection of blood and subsequent quantification of Pb. The protocol of the study was approved by the ethics committee at King Khalid University Hospital, Riyadh, KSA. A volume of 5–7 ml of venous blood was drawn from each child by a registered nurse by use of sealed heparinized, lead-free Vacutainer® tubes (Beckton-Dickinson, USA). Whole blood was stored on ice in coolers and transported on the same day to the laboratory, aliquots of whole blood were stored at −70 °C until analysis. Whole blood was digested in HNO3, HCl, and H202 (30 %) as described by Bukhari et al. (2005). Known volumes of blood samples were placed into a PTFE beaker with 5 ml of concentrated HNO3 and 2 ml of HCl and evaporated on a hot plate at 90–95 °C. When dry a few drops of 30 % H2O2 were added. Digestion was continued until a clear solution was obtained. Digestates were cooled and washed from beakers with water and filtered through 0.45-μm filter paper and the final volume adjusted to 50 ml.
Quantification of Pb by ICP-AES
Concentrations of Pb were determined by use of inductively coupled plasma atomic emission spectroscopy (ICP-AES), by use of an iCAP 6500 ICP-AES (USA) (Thermo Scientific). Concentrations of Pb in digested samples were determined by use of a standard introduction kit (SIK), and a glass concentric nebulizer/cyclonic spray chamber (Henk 2003). The limit of quantification (LOQ) defined as the concentration of Pb that produced three times the average background intensity at the respective wavelengths selected for Pb was 2.5 μg Pb/dl. Accuracy and precision were determined by use of spike-recovery, standard reference materials, replicate analyses, and method blanks. Recovery of Pb and was determined by the use of spike-recovery of split samples. Average recoveries were 98.7 ± 1.1 % with a corresponding CV of 5 %. Accuracy was assessed by analyses of bovine blood standard reference material (NIST 955b) that contained 5.01, 13.53, or 30.63 μg Pb/dl). Samples were analyzed in triplicate with a relative standard deviation of less than 3 %. Concentrations of Pb in method blanks were less than the LOQ.
Statistical analyses
The data were log-transformed prior to conducting statistical tests. The assumptions of normality and homogeneity of variance were confirmed prior to multivariate analysis use of the Kolmogorov–Smirnov and Bartlett tests, respectively. Comparison between means of independent groups was performed using Student’s t test. Differences were considered significant at P < 0.05. Pearson’s coefficients of determination (r 2) were calculated to determine the association between concentrations of Pb in both outdoor and indoor dust and its corresponding concentration in blood. All statistical analyses were conducted using SPSS version 17.0.
Results and discussion
Deposition of outdoor dust varied among seasons in decreasing order: spring (7.1 × 101 ± 1.5 × 101) > summer (6.3 × 101 ± 1.4 × 101) > winter (4.9 × 10−1±2.5) > autumn (4.7 × 101 ± 3.6) tons/km2/month (Table 1). Mean, monthly deposition of outdoor dust averaged across the four seasons was 5.7 × 10−1±1.1 × 10−1 tons km−2, which is equivalent to 690 tons km−2 year−1, which is more than fivefold greater than the WHO limit of 106 tons km−2 year−1 (UNEP 1991). The greater rate of deposition during spring and summer was due to frequent gusty winds and sand storms which primarily take place during these two seasons. In this context, it has been reported that that rates of deposition of dust across Riyadh are affected by distance from construction sites (Modaihsh and Mahjoub 2013). Deposition of dust during winter was 4.9 × 10−1±2.5, which was slightly greater than that of 4.2 × 101 which was reported by Modaihsh and Mahjoub (2013).
Concentrations of Pb in outdoor dust fallout exhibited a similar seasonal pattern of deposition to that observed for dust with decreasing concentrations (Mean ± SD) in: spring (3.1 × 102 ± 1.8 × 101) > summer (2.5 × 102 ± 3.8 × 101) > winter (2.1 × 102 ± 1.2 × 101) > autumn (2.0 × 102 ± 1.1 × 101) μg/g dust (Table 1). The mean concentration of Pb average over the entire year was 2.4 × 102 ± 4.4 × 101. Concentrations of Pb at certain locations were influenced by their proximity sources of pollution and local prevailing meteorological conditions at the time of sampling. Concentrations of Pb in dust are also related to several other factors including size of urbanized area, number of people, age of community, and inner and outer locations of a community within a given urbanized area (Mielke et al.2011).
The overall mean concentration of Pb in outdoor dust of 2.4 × 102 μg/g observed in this study was less than the 1.8 × 103 μg Pb/g that had been previously reported for Riyadh (Al-Rajhi et al. 1996). This result might be due the fact that the sampling sites were in the vicinity of an old industrial area and motorways. The lesser concentrations of Pb in outdoor dust of Riyadh could be partially attributed to the decision of KSA to phase-out leaded gasoline in January 2001 (United Nations and Profile 2002). However, some other cities in the Kingdom have been recently reported to have greater concentrations of Pb in the atmosphere. For example, the concentration of Pb in 2.5 μm (PM2.5) particulates in the air of Jeddah was 2.1 × 103 μg Pb/g (Table 2) (Aburas et al. 2011). PM in the atmosphere originates primarily from activities of humans, such as vehicle exhausts, industrial emissions, construction, and waste treatment. Hence, this greater concentration of Pb in dust in the atmospheric could be explained by the proximity of sampling sites to industrial zones and greater densities of traffic (Aburas et al. 2011). When compared to other cities in the Arabian Gulf region, concentrations of Pb in outdoor dust in Riyadh were greater than that reported for Muscat/Oman (1.1 × 102 μg/g; Yaghi and Abdul-Wahab 2004), but lesser than that reported for Amman/Jordan (2.6 × 102 μg/g; Al-Khashman 2007). Concentrations of Pb in outdoor dust in Riyadh were lesser than that reported for some cities including Torreòn/Mèxico (4.4 × 103 μg/g; Soto-Jimènez and Flegal 2011), London/UK (2.0 × 103 μg/g, Fergusson and Ryan 1984), Madrid/Spain (1.9 × 103 μg/g; DeMiguel et al. 1997), Christchurch/New Zealand (1.2 × 103 μg/g; Fergusson et al. 2003), Paris/France (5.4 × 102 μg/g; Pagotto et al. 2001), Calcutta/India (5.4 × 102 μg/g; Chatterjee and Banerjee 1999), and Baoji/China (4.1 × 101 μg/g; Lu et al. 2009).
Deposition of indoor dust also varied among seasons in decreasing order: spring (6.7 ± 0.66 > summer (5.2 ± 1.8) > winter (3.4 ± 1.3) > autumn (2.7 ± 0.70) tons/km2/month (Table 3). Mean, monthly deposition of indoor dust averaged across the four seasons was 4.5 ± 1.8 tons km−2. Concentrations of Pb in indoor dust fallout exhibited a similar seasonal pattern of deposition to that observed for dust with decreasing concentrations in: spring (5.1 × 101 ± 1.8 × 101) > summer (3.4 × 101 ± 7.7) > winter (2.2 × 101 ± 1.2 × 101) > autumn (1.1 × 101 ± 4.8) μg/g dust (Table 3). The mean concentration of Pb averaged over the entire year was 2.9 × 101 ± 1.5 × 101. The reported mean indoor Pb concentration in Riyadh city has been compared to other cities (Table 4). The mean concentration of Pb (2.9 × 101 ± 1.5 × 101) in indoor dust fall on Riyadh, which is reported in the current study, was lesser than that previously reported for Riyadh (6.4 × 102 μg/g, Al-Rajhi et al. 1996) and other cities in the Arabian Gulf region such as Oman (6.5 × 101 μg/g, Yaghi and Abdul-Wahab 2004) and Bahrain (7.0 × 102 μg/g, Akhter and Madany 1993). Similarly, the mean concentration of Pb in indoor dust fall on Riyadh was lesser when compared to that in other cities (Table 4), including Cincinnati/USA (3.8 × 102 μg/g, Tong 1998), Ottawa/Canada (6.2 × 102 and 2.7 × 102 μg/g, Rasmussen et al. 2001), UK (5.6 × 102, Thornton et al. 1990), Hellstead/Germany (1.3 × 102 μg/g, Meyer et al. 1999), Sydney/Australia (3.9 × 102 μg/g, Chattopadhyay et al. 2003), Hong Kong/China (1.6 × 102 μg/g, Tong and Lam 2000), and Torreòn/Mèxico (3.1 × 103 μg/g, Soto-Jimènez and Flegal 2011).
Indoor dust is related to outdoor dust and thus results in greater concentrations of Pb in indoor dust. Contaminated dust can be brought into homes by shoes (Hunt et al. 2006), family pets, and also via re-suspension and deposition of Pb in dust on contact surfaces (Layton and Beamer 2009). The results of the present study were not in agreement with other studies of Pb in Riyadh, which have reported greater concentrations of Pb in indoor dust than in outdoor dust samples in urban, suburban, and rural areas (Al-Shayeb and Seaward 2000, Bounessah et al. 2001). It has been reported that a portion of interior house dust most probably originates from outdoor soils. This demonstrates the importance of soil and dust as potential exposure pathways for exposure of children to Pb (Paustenbach et al. 1997). Hence, based on our results and those of others, there is a positive relationship between Pb in outdoor and indoor dusts, which indicates their significance as common sources of anthropogenic activities.
In this study, there were significant (P < 0.01) correlations between concentrations of Pb and the quantity of outdoor and indoor dust fall (r 2 0.43, P < 0.00 and r 2 0.37, P < 0.003, respectively), but there was no correlation between concentrations of Pb in indoor dust and concentrations of Pb in blood of children from Riyadh. There was, however, a significant (P < 0.05) correlation between the concentration of Pb in outdoor dust and that of blood of children (r 2 0.077, P < 0.045). While there was a statistically significant relationship between concentrations of Pb in blood of children and concentrations of Pb in outdoor dust, the relationship was weak, explaining only 7 % of the variance in concentrations of Pb in blood. Also, based on logic, if the concentration of Pb in indoor and outdoor dust is significantly correlated (r 2 0.43, P < 0.00 and r 2 0.37, P < 0.003, respectively) and the concentration of Pb in outdoor dust is correlated with the concentration of Pb in blood, one would expect that there would also be an association between concentrations of Pb in indoor dust and blood. Based on this assessment of the data, it can be concluded that there is little or no relationship between concentrations of Pb in dust and that in blood of children. Since concentrations of Pb in blood of more than 17.8 % of children in Riyadh exceed the guideline proposed by CDC (CDC 2005), alternative sources of Pb should be identified so that appropriate remedial measures can be taken to further reduce concentrations of Pb in blood of children and ameliorate the potential for effects on neurobehavioral development. It has been shown previously that the concentration of Pb in blood of children was directly related to concentrations of Pb in dust (Stark et al. 1982). It has been estimated that a concentration of 1,000 μg Pb/g in dust would result in a concentration of 5 μg/dl of Pb in blood (Stark et al. 1982). In this study, concentrations of Pb in whole blood of 300, 6–12-year-old children living in Riyadh had a mean concentration of 5.2 ± 1.7 μg Pb/dl, with a range of 1.7–1.5 × 101 μg/dl. Moreover, concentrations of Pb in blood of 17.8 % of the screened children exceeded the 10 μg/dl, the US Centers for Disease Control (CDC)’s level of concern (CDC 2005). It has been reported previously that the mean concentration of Pb in whole blood of 6–12-year-old school girls was 8.1 ± 3.5 with a range of 2.3–2.7 × 101 μg/dl (Al-Saleh et al. 2001). The same researchers also reported an association between neuropsychological and behavioral impairment and concentrations of Pb in whole blood in the range of 9.0–2.7 × 101 μg/l (Al-Saleh et al. 2001). Exposures to Pb can result in significantly lesser intelligence quotients (IQ) of children. For example, it is estimated that every 1.0 × 102 μg Pb/dl increase in concentration of Pb in whole blood is associated with a 1- to 5-point decrease in IQ of exposed children (Goyer 1996). It has also been reported that 24.4 % of Saudi school girls had concentrations of Pb in whole blood that exceeded 10 μg/dl, which is the level of concern set by the US Centers for Disease Control (CDC) (Al-Saleh et al. 1999). Recently, the CDC uses the term “reference value” that replaces the term “level of concern.” The CDC’s reference value is described as the blood lead level of ≥97.5 percentile of the US childhood population (Advisory Committee on Childhood Lead Poisoning Prevention 2012; CDC 2012). The observed reduction in the proportion of Saudi children exposed to Pb is most likely a direct result of the decision of phasing-out leaded gasoline taken by the Saudi authorities in January 2001 (United Nations and Profile 2002). However, the appropriateness of the CDC’s current guideline of 10 μg Pb/dl has recently been questioned (Kordas et al. 2006). For instance, school pupils with concentrations of <10 μg Pb/dl in their blood have been reported to have deficits in cognitive function, nonverbal reasoning, memory, and achievement (Kordas et al. 2006).
Based on the Saudi Arabian Standard Organization (SASO), the current specification of unleaded gasoline in Saudi Arabia stipulates a maximum Pb content of 0.013 g/l (Aburas et al. 2011). However, the rate of consumption is associated with the social and economic growth in the Kingdom. Hence, even use of unleaded gasoline could potentially contribute toward the total emissions of Pb to the atmosphere (Xiaolin et al. 2009). Therefore, more efforts are needed to help understand all sources of Pb to the atmosphere and their potential contribution to concentrations of Pb in outdoor and indoor dust in the KSA. There is an urgent need for establishment of a systematic Kingdom-wide program to monitor for concentrations of Pb in soils, especially in urban areas of the KSA and to assess the associated risks posed by environmental exposure of Pb to urban populations, especially children.
References
Abdul Wahab, N. A., Darus, F. M., Isa, N., Sumari, S. M., & Hanafi, N. F. M. (2012). Heavy metals concentration of settled surface dust in residential building. The Malaysian Journal of Analytical Sciences, 16(1), 18–23.
Aburas, H. M., Zytoon, M. A., & Abdulsalam, M. I. (2011). Atmospheric lead in PM2.5 after leaded gasoline phase-out in Jeddah city, Saudi Arabia. Clean–Soil, Air Water, 39(8), 711–719.
Advisory Committee on Childhood Lead Poisoning Prevention (2012). Low level lead exposure harms children: A renewed call for primary prevention. Atlanta, GA: US Department of Health and Human Services, CDC, Advisory Committee on Childhood Lead Poisoning Prevention; [http://www.cdc.gov/nceh/lead/acclpp/final_document_010412pdf].
Agency for Toxic Substances and Disease Registry (ASTDR) (2011). Priority list of hazardous substances, comprehensive environmental response, compensation, and liability act (CERCLA) (http://www.atsdr.cdc.gov/cercla/).
Ahmed, K. O., Al-Swaidan, H. M., & Davies, B. E. (1993). Simultaneous elemental analysis in dust of the city of Riyadh, Saudi Arabia by inductively coupled plasma–mass spectrometry (ICP/MS). The Science of the Total Environment, 136, 207–212.
Ahmed, F., & Ishiga, H. (2006). Trace metal concentrations in street dusts of Dhaka city, Bangladesh. Atmospheric Environment, 40, 3835–3844.
Akhter, M. S., & Madany, I. M. (1993). Heavy metals in street and house dust in Bahrain Water Air & Soil Pollution, 66, 111–120.
Ali, M. H. H., & Al-Qahtani, K. M. (2012). Assessment of some heavy metals in vegetables, cereals and fruits in Saudi Arabian markets. The Egyptian Journal of Aquatic Research, 38(1), 31–37.
Al-Khashman, O. A. (2007). Determination of metal accumulation in deposited street dusts in Amman, Jordan. Environmental Geochemistry and Health, 29, 1–10.
Al-Othman, Z. A. (2010). Lead contamination in selected foods from Riyadh city market and estimation of the daily intake. Molecules, 15, 7482–7497.
Al-Othman, A. M., Al-Othman, Z. A., El-Desoky, G. E., Aboul-Soud, M. A. M., Habila, M. A., & Giesy, J. P. (2012). Lead in drinking water and human blood in Riyadh City Saudi Arabia. Arabian Journal of Geosciences,. doi:10.1007/s12517-012-0551-4.
Al-Rajhi, M. A., Seaward, M. R. D., & Al-Aemer, A. S. (1996). Metals level indoor and outdoor dust in Riyadh, Saudi Arabia. Environmental International, 22, 315–324.
Al-Saleh, I., Nester, M., DeVol, E., Shinwari, N., & Al-Shahria, S. (1999). Determinants of blood lead levels in Saudi Arabian schoolgirls. International Journal of Occupational & Environmental Health, 5(2), 107–114.
Al-Saleh, I., Nester, M., DeVol, E., Shinwari, N., Munchari, L., & Al-Shahria, S. (2001). Relationships between blood lead concentrations, intelligence, and academic achievement of Saudi Arabian schoolgirls. International Journal of Hygiene and Environmental Health, 204(2–3), 165–174.
Al-Shayeb, S. M., & Seaward, M. R. D. (2000). The date palm (Phoenix dactylifera L.) fibre as a biomonitor of lead and other elements in arid environments. Asian Journal of Chemistry, 12, 954–966.
Bounessah, M., Al-Shayeb, S. M., Al-Ghefaili, K. M., & Abdulfatah, B. (2001). Assessment of lead levels in dust and date palm (Phoenix dactylifera L.) in 6-10 year-old school children environment in Riyadh city Saudi-Arabia. Asian Journal of Chemistry, 13, 1435–1442.
Bukhari, I. H., Hassan, M. N., Haleem, A., & Maqbool, M. B. (2005). Role of metals (cadmium and lead) in patients of hypertension and their relationship with Ischemic Heart Disease. Research Journal of Agricultural & Biological Science, 1, 190–194.
CDC (2005). Blood lead levels—United States, 1999–2002. Morbidity and mortality. Weekly Report Recommendations and Reports Weekly, 54 (20), 513e516. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5420a5.htm.
CDC (2012). Response to advisory committee on childhood lead poisoning prevention recommendations in low level lead exposure harms children: A renewed call for primary prevention. Atlanta, GA: US Department of Health and Human Services; [MMWR 61(20):383.
Chatterjee, A., & Banerjee, R. N. (1999). Determination of lead and other metals in a residential area of greater Calcutta. The Science of the Total Environment, 227, 175–185.
Chattopadhyay, G., Lin, K. C. P., & Feitz, A. J. (2003). Indoor dust metal levels in the Sydney metropolitan area. Environmental Research, 93, 301–307.
DeMiguel, E., Llamas, J. F., Chacon, E., Berg, T., Larssen, S., Røyset, O., et al. (1997). Origin and patterns of distribution of trace elements in street dust: unleaded petrol and urban lead. Atmospheric Environment, 3117, 2733–2740.
El-Shobokshy, M. S. (1984). A preliminary analysis of the inhalable particulate lead in the ambient atmosphere of the city of Riyadh, Saudi Arabia. Atmospheric Environment, 18, 2125–2130.
El-Shobokshy, M. S., Al-Tamrah, S. A., & Hussein, F. M. (1990). Inhalable particulates and meteorological characteristics of the city of Riyadh, Saudi Arabia. Atmospheric Environment Part B Urban Atmosphere, 24B, 261–265.
Ewen, C., Anagnostopoulou, M. A., & Ward, N. I. (2009). Monitoring of heavy metal levels in roadside dusts of Thessaloniki, Greece in relation to motor vehicle traffic density and flow. Environmental Monitoring and Assessment, 157(1–4), 483–498.
Fergusson, E., Forbes, E. A., Schroeder, R. J., & Ryan, D. E. (2003). The elemental composition and sources of house dust and street dust. Science of the Total Environment, 50, 217–221.
Fergusson, J. E., & Ryan, D. E. (1984). The elemental composition of street dust from large and small urban areas related to city type, source and particle size. Science of the Total Environment, 34, 101–116.
Ferreira-Baptista, L., & De Miguel, E. (2005). Geochemistry and risk assessment of street dust in Luanda, Angola: A tropical urban environment. Atmospheric Environment, 39, 4501–4512.
Gibson, J. L. (1904). A plea for painted railings and painted rooms as the source of lead poisoning amongst Queensland children. Australasian Medical Gazette, 23, 149–153.
Goyer, R. A. (1996). Results of lead research: Prenatal exposure and neurological consequences. Environmental Health Perspectives, 104(10), 1050.
Henk, J. W. (2003). Determination of elements by ICP-AES and ICP-MS; National Institute of Public Health and the Environment (RIVM): Bilthoven, The Netherlands. (http://www.ecn.nl/docs/society/horizontal/hor_desk_19_icp.pdf).
Hjortenkrans, D., Bergback, B., & Haggerud, A. (2006). New metal emission patterns in road traffic environments. Environmental Monitoring and Assessment, 117, 85–98.
Hunt, A., Johnson, D. L., & Griffith, D. A. (2006). Mass transfer of soil indoors by track-in on footwear. Science of the Total Environment, 370, 360–371.
International Energy Agency (IEA) (2010), Energy statistics of non-OECD countries, IEA, Paris.
Klepeis, N. E., Nelson, W. C., Ott, W. R., Robinson, J. P., Tsang, A. M., Switzer, P., et al. (2001). The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants. Journal of Exposure Analysis and Environmental Epidemiology, 11, 231–252.
Kordas, K., Canfield, R. L., López, P., Rosado, J. L., Vargas, G. G., Cebrián, M. E., et al. (2006). Deficits in cognitive function and achievement in Mexican first-graders with low blood lead concentrations. Environmental Research, 100, 371–386.
Laidlaw, M. A. S., Mielke, H. W., Filippelli, G. M., Johnson, D. L., & Gonzales, C. R. (2005). Seasonality and children’s blood lead levels: developing a predictive model using climatic variables and blood lead data from Indianapolis, Indiana, Syracuse, New York, and New Orleans, Louisiana (USA). Environmental Health Perspectives, 113, 793–800.
Laidlaw, M. A. S., & Taylor, M. P. (2011). Potential for childhood lead poisoning in the inner cities of Australia due to exposure to lead in soil dust. Environmental Pollution, 159, 1–9.
Latif, M. T., Baharudin, N. H., Nor, Z. M., & Mokhtar, M. B. (2011). Lead in PM10 and in indoor dust around schools and preschools in Selangor, Malaysia. Indoor and Built Environment, 20, 346–353.
Layton, D., & Beamer, P. (2009). Migration of contaminated soil and airborne particulates to indoor dust. Environmental Science and Technology, 43, 8199–8205.
Li, X., Poon, C. S., & Liu, P. S. (2001). Heavy metal contamination of urban soils and street dusts in Hong Kong. Applied Geochemistry, 16, 1361–1368.
Lu, X., Wanga, L., Lei, K., Huang, J., & Zhai, Y. (2009). Contamination assessment of copper, lead, zinc, manganese and nickel in street dust of Baoji, NW China. Journal of Hazardous Materials, 161, 1058–1062.
Meyer, I., Heinrich, J., & Lippold, U. (1999). Factors affecting lead cadmium and arsenic levels in house dust in a smelter town in eastern Germany. Environmental Research, 81, 32–44.
Mielke, H. W., Gonzales, C. R., & Mielke, P. W., Jr. (2011). The continuing impact of lead dust on children’s blood lead: Comparison of public and private properties in New Orleans. Environmental Research, 111, 1164–1172.
Modaihsh, A. S., & Mahjoub, M. S. (2013). Falling dust characteristics in Riyadh city, Saudi Arabia during Winter months. Asia-Pacific Chemical, Biological & Environmental Engineering Society, APCBEE Procedia, 5, 50–58.
Pagotto, C., Rémy, N., Legret, M., & Le Cloirec, P. (2001). Heavy metal pollution of road dust and roadside soil near a major rural highway. Environmental Technology, 22, 307–319.
Paustenbach, D. J., Finley, B. L., & Long, T. F. (1997). The critical role of house dust in understanding the hazards posed by contaminated soils. International Journal of Toxicology, 16, 339–362.
Rasmussen, P. E., Subramanian, K. S., & Jessiman, B. J. (2001). A multi-element profile of house dust in relation to exterior dust and soils in the city of Ottawa, Canada. Science of the Total Environment, 267, 125–1140.
Robertson, D. J., Taylor, K. G., & Hoon, S. R. (2003). Geochemical and mineral magnetic characterization of urban sediment particulates, Manchester, UK. Applied Geochemistry, 18, 269–282.
Saudi Centeral Department of Statistics and Information (CDSI) (2007). Demographic survey http://www.cdsi.gov.sa/english/.
Sezgin, N., Ozcan, H. K., Demir, G., Nemlioglu, S., & Bayat, C. (2003). Determination of heavy metal concentrations in street dusts in Istanbul E-5 highway. Environment International, 29, 979–985.
Sharpe, M. (2004). Safe as houses? Indoor air pollution and health. Journal of Environmental Monitoring, 6, 46–49.
Shi, G., Chen, S., Xu, S., Zhang, J., Wang, C., & Bi, J. (2008). Potentially toxic metal contamination of urban soils and roadside dust in Shanghai, China. Environmental Potential, 156, 251–260.
Soto-Jimènez, M. F., & Flegal, R. A. (2011). Childhood lead poisoning from the smelter in Torreòn, Mèxico. Environmental Research, 111, 590–596.
Sow, M., Goossens, D., & Rajot, J.-L. (2006). Calibration of the MDCO dust collector and of four versions of the inverted frisbee dust deposition sampler. Geomorphology, 82(3–4), 360–375.
Stark, A. D., Quah, R. F., Meigs, J. W., & DeLouise, E. R. (1982). The relationship of environmental lead to blood-lead levels in children. Environmental Research, 27(2), 372–383.
Tahir, N. M., Poh, S. C., & Jaafar, M. (2007). Determination of heavy metal contents in soils and indoor dusts from nurseries in Dungun, Terengganu. The Malaysian Journal of Analytical Sciences, 11, 280–286.
Thornton, I., Davies, D. J. A., Watt, J. M., & Quinn, M. J. (1990). Lead exposure in young children from dust and soil in the United Kingdom. Environmental Health Perspective, 89, 55–60.
Tong, S. T. Y. (1998). Indoor and outdoor household dust contamination in Cincinnati, Ohio USA. Environmental Geochemistry and Health, 20(3), 123–133.
Tong, S. T. Y., & Lam, K. C. (2000). Home sweet home? A case study of indoor dust contamination in Hong Kong. The Science of the Total Environment, 256, 115–123.
UNEP (1991). Urban air pollution, UNEP/GEMS Environment Library, No. 4.
United Nations, UN Country Profile (2002): Saudi Arabia, United Nations, The World Summit on Sustainable Development, Johannesburg.
United States Department of Health and Human Services (USDHHS) (2012). National Toxicology Program. Monograph on health effects of low-level lead; [http://ntp.niehs.nih.gov/go/36443].
United States Environmental Protection Agency (USEPA) (1994). Guidance on residential lead based paint, lead-contaminated dust, and lead-contaminated soil. Memorandum from Lynn R. Goldman, Assistant Administrator of the Office of Prevention, Pesticides and Toxic Substances, US Environmental Protection Agency.
WHO. (2002). Initiating an alliance for action: Healthy environments for children. Geneva: World Health Organization.
Xiaolin, L. I., Yuanxun, Z., Mingguang, T., Jiangfeng, L., Liangman, B., Juilin, Z., et al. (2009). Atmospheric lead pollution in fine particulate matter in Shanghai China. Journal of Environmental Sciences, 21(8), 11–18.
Yaghi, B., & Abdul-Wahab, S. A. (2004). Levels of heavy metals in outdoor and indoor dusts in Muscat Oman. International Journal of Environmental Studies, 61(3), 307–314.
Yeung, Z. L. L., Kwok, R. C. W., & Yu, K. N. (2003). Determination of multi-element profiles of street dust using energy dispersive X-ray fluorescence EDXRF. Applied Radiation and Isotopes, 58, 339–346.
Acknowledgments
The authors extend their appreciation to the Deanship of Scientific Research at King Saud University for funding the work through the research group project No RGP-VPP-130. Prof. Giesy was supported by the Canada Research Chair program, a Visiting Distinguished Professorship in the Department of Biology and Chemistry and State Key Laboratory in Marine Pollution, City University of Hong Kong, the 2012 “High Level Foreign Experts” (#GDW20123200120) program, funded by the State Administration of Foreign Experts Affairs, the P.R. China, to Nanjing University and the Einstein Professor Program of the Chinese Academy of Sciences.
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El-Desoky, G.E., Aboul-Soud, M.A.M., Al-Othman, Z.A. et al. Seasonal concentrations of lead in outdoor and indoor dust and blood of children in Riyadh, Saudi Arabia. Environ Geochem Health 36, 583–593 (2014). https://doi.org/10.1007/s10653-013-9582-3
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DOI: https://doi.org/10.1007/s10653-013-9582-3