Abstract
Glutathione metabolism and its role in vital functions of bacterial cells are considered, as well as common features and differences between the functions of glutathione in prokaryotic and eukaryotic cells. Particular attention is given to the recent data for the role of glutathione in bacterial redox-regulation and adaptation to stresses.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Abbreviations
- GSH:
-
reduced glutathione
- GSSG:
-
oxidized glutathione
- GOR:
-
glutathione oxidoreductase
- CoA:
-
coenzyme A
- Grx:
-
glutaredoxin
- Dsb:
-
periplasmic redox proteins
- NEM:
-
N-ethylmaleimide
- GST:
-
glutathione S-transferase
- Msc:
-
mechanosensitive ion channels
- PcpC:
-
tetrachloro-p-hydroquinone dehydrogenase
- ROS:
-
reactive oxygen species
REFERENCES
Fahey, R. C., Brown, W. C., Adams, W. B., and Worsham, M. B. (1978) J. Bacteriol., 133, 1126–1129.
Newton, G. L., Arnold, K., Price, M. S., Sherrill, C., delCardayre, S. B., Aharonowitz, Y., Cohen, G., Davies, J., Fahey, R. C., and Davis, C. (1996) J. Bacteriol., 178, 1990–1995.
Sherrill, C., and Fahey, R. C. (1998) J. Bacteriol., 180, 1454–1459.
Vergauwen, B., Pauwels, F., Vaneechoutte, M., and van Beeumen, J. J. (2003) J. Bacteriol., 185, 1572–1581.
Sundquist, A. R., and Fahey, R. C. (1989) J. Mol. Evol., 29, 429–435.
Kosower, N. S., and Kosower, E. M. (1978) Int. Rev. Cytol., 54, 109–160.
Meister, A., and Anderson, M. E. (1983) Ann. Rev. Biochem., 52, 711–760.
Gushima, H., Miya, T., Murata, K., and Kimura, A. (1983) J. Appl. Biochem., 5, 210–218.
Murata, K., and Kimura, A. (1990) Biotech. Adv., 8, 5–96.
Matsuda, K., Mizuguchi, K., Nishioka, T., Kato, H., Go, N., and Oda, J. (1996) Protein Eng., 9, 1083–1092.
Hibi, T., Hisada, H., Nakatsu, T., Kato, H., and Oda, J. (2002) Acta Crystallogr. Sec. D-Biol. Crystallogr., 58, 316–318.
Apontoweil, P., and Berends, W. (1975) Biochim. Biophys. Acta, 399, 10–22.
Greenberg, J. T., and Demple, B. (1986) J. Bacteriol., 168, 1026–1029.
Loewen, P. C. (1979) Can. J. Biochem., 57, 107–111.
Park, S., and Imlay, J. A. (2003) J. Bacteriol., 185, 1942–1950.
Suzuki, H., Kamatani, S., Kim, E. S., and Kumagai, H. (2001) J. Bacteriol., 183, 1489–1490.
Suzuki, H., Kumagai, H., and Tochikura, T. (1986) J. Bacteriol., 168, 1325–1331.
Suzuki, H., Kumagai, H., and Tochikura, T. (1987) J. Bacteriol., 169, 3926–3931.
Suzuki, H., Kumagai, H., Echigo, T., and Tochikura, T. (1989) J. Bacteriol., 171, 5169–5172.
Xu, K., and Strauch, M. A. (1996) J. Bacteriol., 178, 4319–4322.
Parry, J., and Clark, D. P. (2002) FEMS Microbiol. Lett., 209, 81–85.
Davis, N. K., Greer, S., Jones-Mortimer, M. C., and Perham, R. N. (1982) J. Gen. Microbiol., 128, 1631–1634.
Russel, M., and Holmgren, A. (1988) Proc. Natl. Acad. Sci. USA, 85, 990–994.
Mata, A. M., Pinto, M. C., and Lopez-Barea, J. (1984) Z. Naturforsch., 39, 908–915.
Greer, S., and Perham, R. N. (1986) Biochemistry, 25, 2736–2742.
Christman, M. F., Morgan, R. W., Jacobson, F. S., and Ames, B. N. (1985) Cell, 41, 753–762.
Michan, C., Manchado, M., Dorado, G., and Pueyo, C. (1999) J. Bacteriol., 181, 2759–2764.
Becker-Hapak, M., and Eisenstark, A. (1995) FEMS Microbiol. Lett., 134, 39–44.
Alonso-Moraga, A., Bocanegra, A., Torres, J. M., Lopez-Barea, J., and Pueyo, C. (1987) Mol. Cell. Biochem., 73, 61–68.
Smirnova, G. V., Muzyka, N. G., Glukhovchenko, M. N., and Oktyabrsky, O. N. (2000) Free Rad. Biol. Med., 28, 1009–1016.
Tabor, H. C., and Tabor, W. (1975) J. Biol. Chem., 250, 2648–2654.
Loewen, P. (1977) Can. J. Biochem., 55, 1019–1027.
Loewen, P. C. (1978) Can. J. Biochem., 56, 753–759.
Smirnova, G. V., Torkhova, O. A., and Oktyabrsky, O. N. (2003) Mikrobiologiya, 72, 542–547.
Kosower, E. M., Correa, W., Kinon, B. J., and Kosower, N. S. (1971) Biochim. Biophys. Acta, 264, 39–44.
Hibberd, K. A., Berget, P. B., Warner, H. R., and Fuchs, J. A. (1978) J. Bacteriol., 133, 1150–1155.
Romero, M. J., and Canada, A. T. (1991) Toxicol. Appl. Pharmacol., 111, 485–495.
Meister, A. (1988) J. Biol. Chem., 263, 17205–17208.
Nakayama, R., Kumagai, H., and Tochikura, T. (1984) Appl. Environ. Microbiol., 47, 653–657.
Owens, R. A., and Hartman, P. E. (1986) J. Bacteriol., 168, 109–114.
Owens, R. A., and Hartman, P. E. (1986) Environ. Mutagen., 8, 659–673.
Smirnova, G. V., Muzyka, N. G., and Oktyabrsky, O. N. (2005) Biochemistry (Moscow), 70, 926–934.
Smirnova, G. V., Krasnykh, T. A., and Oktyabrsky, O. N. (2001) Biochemistry (Moscow), 66, 973–978.
Smirnova, G. V., Zakirova, O. N., and Oktyabrsky, O. N. (2001) Mikrobiologiya, 70, 45–50.
Smirnova, G. V., Zakirova, O. N., and Oktyabrsky, O. N. (2001) Mikrobiologiya, 70, 512–518.
Oktyabrsky, O. N., Pshenichnov, R. A., Tkachenko, A. G., Zelenin, E. N., and Smirnova, G. V. (1981) Mikrobiologiya, 50, 467–470.
Oktyabrsky, O. N., and Pshenichnov, R. A. (1982) Mikrobiologiya, 51, 515–517.
Oktyabrsky, O. N., and Smirnova, G. V. (1989) Acta Biotechnol., 9, 203–209.
Oktyabrsky, O. N., and Smirnova, G. V. (1993) Bioelectrochem. Bioenerg., 32, 287–294.
Oktiabrsky, O. N., and Smirnova, G. V. (1988) Biokhimiya, 53, 2042–2050.
Oktyabrsky, O. N., Golyasnaya, N. V., Smirnova, G. V., Demakov, V. A., Posokhina, N. Kh., and Kholstova, T. A. (1993) Mutat. Res., DNA Repair, 293, 197–204.
Schafer, F. Q., and Buettner, G. R. (2001) Free Rad. Biol. Med., 30, 1191–1212.
Holmgren, A., and Aslund, F. (1995) Meth. Enzymol., 252, 283–292.
Aslund, F., Ehn, B., Miranda-Vizuete, A., Pueyo, C., and Holmgren, A. (1994) Proc. Natl. Acad. Sci. USA, 91, 9813–9817.
Zheng, M., Aslund, F., and Storz, G. (1998) Science, 279, 1718–1721.
Aslund, F., Zheng, M., Beckwith, J., and Storz, G. (1999) Proc. Natl. Acad. Sci. USA, 96, 6161–6165.
Russel, M., and Holmgren, A. (1988) Proc. Natl. Acad. Sci. USA, 85, 990–994.
Prinz, W. A., Aslund, F., Holmgren, A., and Beckwith, J. (1997) J. Biol. Chem., 272, 15661–15667.
Vlamis-Gardikas, A., Potamitou, A., Zarivach, R., Hochman, A., and Holmgren, A. (2002) J. Biol. Chem., 277, 10861–10868.
Arner, E. S. J., and Holmgren, A. (2000) Eur. J. Biochem., 267, 6102–6109.
Gleason, F. K., and Holmgren, A. (1988) FEMS Microbiol. Rev., 54, 271–298.
Russel, M., and Model, P. (1985) Proc. Natl. Acad. Sci. USA, 82, 29–33.
Carmel-Harel, O., and Storz, G. (2000) Annu. Rev. Microbiol., 54, 439–461.
Potamitou, A., Holmgren, A., and Vlamis-Gardikas, A. (2002) J. Biol. Chem., 277, 18561–18567.
Miranda-Vizuete, A., Rodriguez-Ariza, A., Toribio, F., Holmgren, A., Lopez-Barea, J., and Pueyo, C. (1996) J. Biol. Chem., 271, 19099–19103.
Ritz, D., and Beckwith, J. (2001) Annu. Rev. Microbiol., 55, 21–48.
Paget, M. S. B., and Buttner, M. J. (2003) Annu. Rev. Genet., 37, 91–121.
Klatt, P., and Lamas, S. (2000) Eur. J. Biochem., 267, 4928–4944.
Gilbert, H. F. (1982) J. Biol. Chem., 257, 12086–12091.
Ziegler, D. M. (1985) Ann. Rev. Biochem., 54, 305–329.
Ondarza, R. N. (1989) Biosci. Rep., 9, 593–604.
Thomas, J. A., Poland, B., and Honzatko, R. (1995) Arch. Biochem. Biophys., 319, 1–9.
Jung, C. H., and Thomas, J. A. (1996) Arch. Biochem. Biophys., 335, 61–72.
Lillig, C. H., Potamitou, A., Schwenn, J. D., Vlamis-Gardikas, A., and Holmgren, A. (2003) J. Biol. Chem., 278, 22325–22330.
Kim, S. O., Merchant, K., Nudelman, R., Beyer, W. F., Jr., and Keng, T. (2002) Cell, 109, 383–396.
Epstein, W., Buurman, E., McLaggan, D., and Naprstek, J. (1993) Biochem. Trans., 21, 1006–1610.
Meury, J., and Kepes, A. (1982) EMBO J., 1, 339–343.
Booth, I. R., Jones, M. A., McLaggan, D., Nikolaev, Y., Ness, L. S., Wood, C. M., Miller, S., Totemeyer, S., and Ferguson, G. P. (1996) in Handbook of Biological Physics, Vol. 2 (Konings, W. N., Kabac, H. R., and Lolkema, J. S., eds.) Elsevier Science, pp. 693–729.
Ferguson, G. P., McLaggan, D., and Booth, I. R. (1995) Mol. Microbiol., 17, 1025–1033.
Ness, L. S., Ferguson, G. P., Nikolaev, Y., and Booth, I. R. (1997) Appl. Environ. Microbiol., 63, 4083–4086.
Elmore, M. J., Lamb, A. J., Ritchie, G. Y., Douglas, R. M., Munro, A., Gajewska, A., and Booth, I. R. (1990) Mol. Microbiol., 4, 405–412.
Ferguson, G. P., and Booth, I. R. (1998) J. Bacteriol., 180, 4314–4318.
McLaggan, D., Jones, M. A., Gouesbet, G., Levina, N., Lindey, S., Epstein, W., and Booth, I. R. (2002) Mol. Microbiol., 43, 521–536.
Koprowski, P., and Kubalski, A. (1999) Eur. J. Physiol., 438, 361–364.
Vuilleumier, S. (1997) J. Bacteriol., 179, 1431–1441.
Perito, B., Allocati, N., Casalone, E., Masulli, M., Dragani, B., Polsinelli, M., Aceto, A., and Ilio, C. D. (1996) Biochem. J., 318, 157–162.
Nishida, M., Kong, K. H., Inoue, H., and Takahashi, K. (1994) J. Biol. Chem., 269, 32536–32541.
McLaggan, D., Rufino, H., Jaspars, M., and Booth, I. R. (2000) Appl. Environ. Microbiol., 66, 1393–1399.
Kaluzna, A., and Bartosz, G. (1997) Biochem. Mol. Biol. Int., 43, 161–171.
Mannervik, B., Carlberg, I., and Larson, K. (1989) in Glutathione: Chemical, Biochemical and Medical Aspects, Pt. A, B (Dolphin, D., Poulson, R., and Avramovic, D., eds.) N. Y., pp. 476–516.
Cooper, R. A. (1984) Annu. Rev. Microbiol., 38, 49–68.
Murata, K., Tani, K., Kato, J., and Chibata, I. (1980) J. Gen. Microbiol., 120, 515–517.
Gachhui, R., Pahan, K., Ray, S., Chaudhuri, J., and Mandal, A. (1991) Bull. Environ. Contam. Toxicol., 46, 336–342.
Turner, R. J., Aharonowitz, Y., Weiner, J. H., and Taylor, D. E. (2001) Can. J. Microbiol., 47, 33–40.
Latinwo, L. M., Donald, C., Ikediobi, C., and Silver, S. (1998) Biochem. Biophys. Res. Commun., 242, 67–70.
Chesney, J. A., Eaton, J. W., and Mahoney, J. R., Jr. (1996) J. Bacteriol., 178, 2131–2135.
Saby, S., Leroy, P., and Block, J. C. (1999) Appl. Environ. Microbiol., 65, 5600–5603.
Lawley, P. D., and Thatcher, C. J. (1970) Biochem. J., 116, 693–707.
Sedgwick, B., and Robins, P. (1980) Mol. Gen. Genet., 180, 85–90.
Mohn, G. R., de Knijff P., and Baars, A. (1988) Mutat. Res., 11, 25–31.
Perham, R. A., Andersen, M. E., Warren, S. H., Ross, T. M., and Claxton, L. D. (1997) Toxicol. Appl. Pharmacol., 144, 183–188.
Storz, G., and Imlay, J. A. (1999) Curr. Opin. Microbiol., 2, 188–194.
Pomposiello, P. J., and Demple, B. (2002) Adv. Microb. Physiol., 46, 319–341.
Li, Y., Hugenholtz, J., Abee, T., and Molenaar, D. (2003) Appl. Environ. Microbiol., 69, 5739–5745.
Zheng, M., Wang, X., Templeton, L. J., Smulski, D. R., LaRossa, R. A., and Storz, G. (2001) J. Bacteriol., 183, 4562–4570.
Choi, S. J., Kim, H. J., Mukhopadhyay, P., Cho, S., Woo, J. R., Storz, G., and Ryu, S. E. (2001) Cell, 105, 103–113.
Hausladen, A., Privalle, C. T., Keng, T., DeAngelo, J., and Stamler, J. S. (1996) Cell, 86, 719–729.
Prieto-Alamo, M. J., Jurado, J., Gallardo-Madueno, R., Monje-Casas, F., Holmgren, A., and Pueyo, C. (2000) J. Biol. Chem., 275, 13398–13405.
Oktyabrsky, O. N., Smirnova, G. V., and Muzyka, N. G. (2001) Free Rad. Biol. Med., 31, 250–255.
Ross, D., Thor, H., Orrenius, S., and Moldeus, P. (1985) Chem. Biol. Interact., 55, 177–184.
Pomposiello, P. J., Bennik, M. H. J., and Demple, B. (2001) J. Bacteriol., 183, 3890–3902.
Ding, H., and Demple, B. (1996) Proc. Natl. Acad. Sci. USA, 93, 9449–9453.
Ding, H., and Demple, B. (1998) Biochemistry, 37, 17280–17286.
Stark, A. A., Zeiger, E., and Pagano, D. A. (1988) Carcinogenesis, 9, 771–777.
Glatt, H. (1989) Mutagenesis, 4, 221–227.
Martinez, A., Urios, A., and Blanco, M. (1999) Mutat. Res., 446, 205–213.
Paolicchi, A., Dominici, S., Pieri, L., Maellaro, E., and Pompella, A. (2002) Biochem. Pharmacol., 64, 1027–1035.
O'Malley, Y. Q., Reszka, K. J., Spitz, D. R., Denning, G. M., and Britigan, B. E. (2004) Amer. J. Physiol. Lung Cell Mol. Physiol., 287, L94–L103.
Mitchell, J. B., and Russo, A. (1983) Radiat. Res., 95, 471–485.
Sugiyama, K., Kawamura, A., Izawa, S., and Inoue, Y. (2000) Biochem. J., 352, 71–78.
Privalle, C. T., and Fridovich, I. (1987) Proc. Natl. Acad. Sci. USA, 84, 2723–2726.
Davidson, J. F., Whyte, B., Bissinger, P. H., and Schiestl, R. H. (1996) Proc. Natl. Acad. Sci. USA, 93, 5116–5121.
6Zhang, L., Onda, K., Imai, R., Horiuchi, H., and Ohta, A. (2003) Biochem. Biophys. Res. Commun., 307, 308–314.
Wood, J. M. (1999) Microbiol. Mol. Biol. Rev., 63, 230–262.
Larsen, P. I., Sydnes, L. K., Landfald, B., and Strom, A. R. (1987) Arch. Microbiol., 147, 1–7.
Dinnbier, U., Limpinsel, E., Schmid, R., and Bakker, E. P. (1988) Arch. Microbiol., 150, 348–357.
Munro, G. F., Hercules, K., Morgan, J., and Sauerbier, W. (1972) J. Biol. Chem., 247, 1272–1280.
McLaggan, D., Logan, T. M., Lynn, D. G., and Epstein, W. (1990). J. Bacteriol., 172, 3631–3636.
Oktyabrsky, O. N., and Smirnova, G. V. (1993) Biochem. Mol. Biol. Int., 30, 377–383.
Smirnova, G. V., and Oktyabrsky, O. N. (1995) Arch. Microbiol., 163, 76–78.
McLaggan, D., Naprstek, J., Buurman, E. T., and Epstein, W. (1994) J. Biol. Chem., 269, 1911–1917.
Smirnova, G. V., Muzyka, N. G., and Oktyabrsky, O. N. (2000) FEMS Microbiol. Lett., 186, 209–213.
Author information
Authors and Affiliations
Corresponding author
Additional information
__________
Translated from Biokhimiya, Vol. 70, No. 11, 2005, pp. 1459–1473.
Original Russian Text Copyright © 2005 by Smirnova, Oktyabrsky.
Rights and permissions
About this article
Cite this article
Smirnova, G.V., Oktyabrsky, O.N. Glutathione in Bacteria. Biochemistry (Moscow) 70, 1199–1211 (2005). https://doi.org/10.1007/s10541-005-0248-3
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/s10541-005-0248-3