The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction. In 28 days after ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of ventricular septum, although it produced no effect on the density of β1 and β2 adrenoceptors.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 163, No. 5, pp. 570-573, May, 2017
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Gavrilova, S.A., Markov, M.A., Berdalin, A.B. et al. Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax. Bull Exp Biol Med 163, 617–619 (2017). https://doi.org/10.1007/s10517-017-3862-3
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DOI: https://doi.org/10.1007/s10517-017-3862-3