Abstract
Experiments on “stationary aging” cultures of B11dii-FAF28 Chinese hamster cells showed that contact inhibition of cell growth and further culturing of cells in the stationary phase led to continuous inhibition of enzymes realizing poly-ADP-ribosylation of chromatin proteins. Cell density in the monolayer and percentage of damaged cells detected by trypan blue staining decreases during this process.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 141, No. 5, pp. 567–571, May, 2006
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Shram, S.I., Shilovskii, G.A. & Khokhlov, A.N. Poly(ADP-Ribose)-polymerase-1 and aging: Experimental study of possible relationship on stationary cell cultures. Bull Exp Biol Med 141, 628–632 (2006). https://doi.org/10.1007/s10517-006-0238-5
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DOI: https://doi.org/10.1007/s10517-006-0238-5