Abstract
In male rats exposed to repeated stress, the decrease in stress reactivity produced by subcutaneous injection of dehydroepiandrosterone sulfate (recorded by the decrease in stress-induced concentrations of corticosterone and adrenocorticotropic hormone in blood plasma) was observed 1–6 days postinjection and involved central regulatory mechanisms.
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References
A. V. Val'dman, Pharmacology of Neuropeptides: Proceeding of the Institute of Pharmacology of the USSR Academy of Medical Sciences [in Russian], Moscow (1982), pp. 8–30.
T. A. Obut, Byull. Sib. Otd. Ros. Akad. Med. Nauk, 2, 62–68 (1994).
T. A. Obut, M. V. Ovsyukova, and O. P. Cherkasova, Byull. Eksp. Biol. Med., 135, No. 3, 269–271 (2003).
M. V. Ovsyukova, N. N. Kudryavtseva, T. A. Obut, and A. V. Amikishieva, Ros. Fiziol. Zh., 89, No. 5, 598–604 (2003).
W. Arlt, F. Callies, I. Koehler, et al., J. Clin. Endocrinol. Metab., 86, No. 10, 4686–4692 (2001).
J. A. Carr, Brain Res. Bull., 44, No. 1, 19–23 (1997).
M. Homma, T. Onodera, M. Hirabatake, et al., J. Pharm. Pharmacol., 50, No. 10, 1139–1145 (1998).
K. Pacak, M. Palkovits, I. J. Kopin, and D. S. Goldstein, Front. Neuroendocrinol., 16, 89–150 (1995).
Y. Park, I. K. Ho, L. W. Fan, et al., Brain Res., 894, 311–315 (2001).
A. Prasad, M. Imamura, and Ch. Prasad, Physiol. Behav., 62, No. 5, 1053–1057 (1997).
D. S. Reddy and S. K. Kulkarni, Brain Res., 752, 61–71 (1997).
S. R. Sesack and V. M. Pickel, J. Neurosci., 12, 1335–1350 (1992).
B. E. Wright, F. Svec, and J. R. Porter, Int. J. Obes. Relat. Metab. Disord., 19, No. 12, 887–892 (1995).
Y. Yoshida, S. Koide, N. Hirose, et al., Neurosci., 92, No. 4, 1357–1365 (1999).
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 141, No. 5, pp. 507–510, May, 2006
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Obut, T.A., Ovsyukova, M.V. & Cherkasova, O.P. Prolonged decrease in stress reactivity caused by dehydroepiandrosterone sulfate. Bull Exp Biol Med 141, 571–573 (2006). https://doi.org/10.1007/s10517-006-0223-z
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DOI: https://doi.org/10.1007/s10517-006-0223-z