Abstract
PRIAMO (PaRkinson And non Motor symptOms) is an epidemiology study aimed to assess the prevalence and incidence of non-motor symptoms (NMS) in patients with parkinsonism. PRIAMO consists of two phases: (1) a transversal assessment of the prevalence of NMS and (2) a longitudinal observation with two follow-up visits at 12 and 24 months to establish the incidence of NMS. A secondary aim of PRIAMO is to study the relationship between NMS and quality of life. Patients with parkinsonism have been evaluated in 59 Neurology Centres widely distributed throughout Italy. PRIAMO has analysed a total of 1307 patients (out of 1325 initially enrolled). We expect that PRIAMO will substantially help to quantify the burden of NMS in patients with parkinsonism.
Sommario
PRIAMO (PaRkinson And non Motor symptOms) è uno studio epidemiologico con l’obiettivo di valutare prevalenza e incidenza dei sintomi non motori (NMS) in pazienti con parkinsonismi. Lo studio PRIAMO si compone di due fasi: (1) la prima prevede una valutazione trasversale della prevalenza dei NMS e (2) la seconda prevede un’osservazione longitudinale con due visite di follow-up a 12 e 24 mesi per stabilire l’incidenza dei NMS. Obiettivo secondario di PRIAMO è studiare la relazione tra i NMS e la qualityà di vita dei pazienti che ne sono affetti. I pazienti con parkinsonismo sono stati valutati da 59 Centri Neurologici distribuiti su tutto il territorio italiano. In totale nello studio PRIAMO sono stati analizzati 1307 pazienti (rispetto ai 1325 arruolati dai centri). Da questi primi risultati ci aspettiamo che PRIAMO possa aiutarci a quantificare l’impatto dei sintomi non motori in pazienti con parkinsonismo.
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Antonini, A., Colosimo, C., Marconi, R. et al. The PRIAMO study: background, methods and recruitment. Neurol Sci 29, 61–65 (2008). https://doi.org/10.1007/s10072-008-0863-z
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DOI: https://doi.org/10.1007/s10072-008-0863-z