Summary.
The synthesis of 3-aminoimidazo[1,2-a]pyridines and 3-aminoimidazo[1,2-a]pyrazines through a condensation reaction of 2-aminopyridine or 2-aminopyrazine, aldehyde, and alkyl or aryl isocyanide in high yields at room temperature in the presence of silica sulfuric acid is described.
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Shaabani, A., Soleimani, E. & Maleki, A. One-Pot Three-Component Synthesis of 3-Aminoimidazo[1,2-a]pyridines and -pyrazines in the Presence of Silica Sulfuric Acid. Monatsh. Chem. 138, 73–76 (2007). https://doi.org/10.1007/s00706-006-0561-6
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DOI: https://doi.org/10.1007/s00706-006-0561-6