Summary.
We determined the complete genome sequence of Ebola virus subtype Reston (EBO-R) in the Philippines in 1996. The deduced transcriptional signals were highly conserved among Ebola viruses except for the stop signal of L genes. The intergenic regions were composed of 4 to 7 nucleotides, and of 2 characteristic overlaps and a long intergenic region. The glycoprotein (GP) had several amino acid differences from EBO-R isolated in 1989 and 1992. The variety of GP sequences strongly suggests the independent introduction of EBO-R from unknown natural reservoirs in 1996.
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Accepted June 22, 2001 Recevied May 8, 2001
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Ikegami, T., Calaor, A., Miranda, M. et al. Genome structure of Ebola virus subtype Reston: differences among Ebola subtypes. Arch. Virol. 146, 2021–2027 (2001). https://doi.org/10.1007/s007050170049
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DOI: https://doi.org/10.1007/s007050170049