Background.
Metastatic tumors to the brain presenting exclusively in the choroid plexus are exceedingly rare. These events are frequently associated with renal cell carcinoma (RCC), of which all reported cases have been solitary lesions.
Method. The authors present the unusual case of a patient with metastatic RCC who developed bilateral tumors of the choroid plexus. These tumors, one of which was confirmed to be metastatic RCC by histologic analysis, were treated over a 5-year period with a combination of interventions, including surgical resection, stereotactic radiosurgery, and chemotherapy, in conjunction with continual radiological monitoring.
Findings. Follow-up over a 5-year period demonstrated good control of the patient’s intracranial disease and very little neurologic sequelae.
Interpretation. This strategy was successful in keeping the patient in good health with minimal neurological symptoms, despite the bilateral nature of the disease and its generally poor prognosis.
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Published online July 25, 2003
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Hillard, V., Musunuru, K., Hasan, I. et al. Long-term management of bilateral metastases of renal cell carcinoma to the choroid plexus. Acta Neurochir 145, 793–797 (2003). https://doi.org/10.1007/s00701-003-0061-y
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DOI: https://doi.org/10.1007/s00701-003-0061-y