Abstract.
Bone graft substitutes may be broadly classified as mineralized and demineralized preparations. This article reviews the basic science and biology underlying each preparation. A review of the clinical and experimental applications of each preparation follows. The text concludes with a review of growth factors as biological supplements.
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Berven, S., Tay, B.K., Kleinstueck, F.S. et al. Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation. Eur Spine J 10 (Suppl 2), S169–S177 (2001). https://doi.org/10.1007/s005860100270
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DOI: https://doi.org/10.1007/s005860100270