Abstract
A purified 41-kDa protein of the rodent filaria Acanthocheilonema viteae was shown to protect jirds against a challenge infection. Subcutaneous immunization with the protein reduced the number of adult worms by up to 65 % and the number of circulating microfilariae declined by up to 93 % in these animals. The protein is located in the muscle tissues of adult worms and was identified as tropomyosin by N-terminal sequencing of the purified protein.
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Received: 15 August 1996 / Accepted: 5 October 1996
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Hartmann, S., Adam, R., Marti, T. et al. A 41-kDa antigen of the rodent filaria Acanthocheilonema viteae with homologies to tropomyosin induces host-protective immune responses. Parasitol Res 83, 390–393 (1997). https://doi.org/10.1007/s004360050269
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DOI: https://doi.org/10.1007/s004360050269