Abstract
We report an unusual case of paternity testing from residues of chorionic villi 5 weeks after pregnancy termination. The autopsy of a 32-year-old female homicide victim revealed the presence of intact chorionic villi at the former placenta implantation site. Fetal cells were selectively isolated by laser-induced microdissection of the remaining villi to avoid contamination with maternal DNA. Simultaneous amplification of 12 STR loci in 2 PCR reactions resulted in a combined probability of paternity of 99.94%. This case demonstrates that laser-assisted microdissection and multiplex STR typing provide tools for paternity testing performed on endometrial mucosa long after the product of conception was removed by therapeutic abortion.
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Received: 2 May 2000 / Accepted: 7 November 2000
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Bauer, M., Thalheimer, A. & Patzelt, D. Paternity testing after pregnancy termination using laser microdissection of chorionic villi. Int J Leg Med 116, 39–42 (2002). https://doi.org/10.1007/s004140000197
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DOI: https://doi.org/10.1007/s004140000197