Abstract
We studied 33 patients with astrocytomas of different grades (68 examinations) by magnetic resonance imaging (MRI) and proton MR spectroscopy (1H-MRS). We found that in 80% of the spectra, the presence of signals in the area of 0.8–1.5 ppm, assigned to lipids/lactate in 1H-MR spectra, correlated with signal enhancement after Gd-DTPA administration. We suggest that visibility of lipid/lactate signals could be due to blood–brain barrier damage, which is characterized by contrast agent enhancement.
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Received: 16 November 1998
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Dezortová, M., Hájek, M., Čáp, F. et al. Comparison of MR spectroscopy and MR imaging with contrast agent in children with cerebral astrocytomas. Child's Nerv Syst 15, 408–412 (1999). https://doi.org/10.1007/s003810050426
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DOI: https://doi.org/10.1007/s003810050426