Abstract
Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget’s disease. The effect is seen at lower doses in Paget’s disease than in osteoporosis. Several cases of spontaneous fractures occurring in unaffected bones of Paget’s patients have been reported. However, we believe the case described here is the most severe example of etidronate-induced osteomalacia published in the literature, featuring widespread vertebral collapse occurring as a consequence of nearly 10 years of uninterrupted etidronate treatment for isolated hemipelvic Paget’s disease.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Author information
Authors and Affiliations
Additional information
Received: 9 August 1999 Revision requested: 19 October 1999 Revision received: 6 December 1999 Accepted: 8 December 1999
Rights and permissions
About this article
Cite this article
MacGowan, J., Pringle, J., Morris, V. et al. Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget’s disease. Skeletal Radiol 29, 279–282 (2000). https://doi.org/10.1007/s002560050608
Issue Date:
DOI: https://doi.org/10.1007/s002560050608