Abstract
Cultures of the fungi Aspergillus niger, Cunninghamella verticillata, and Penicillium simplicissimum, grown in a sucrose/peptone medium, transformed N-acetylphenothiazine to N-acetylphenothiazine sulfoxide (from 13% to 28% of the total) and phenothiazine sulfoxide (from 5% to 27%). Phenothiazin-3-one (4%) and phenothiazine N-glucoside (4%) were also produced by C. verticillata. The probable intermediate, phenothiazine, was detected only in cultures of P. simplicissimum (6%).
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Received: 15 January 1999 / Received revision: 7 May 1999 / Accepted: 21 May 1999
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Parshikov, I., Freeman, J., Williams, A. et al. Biotransformation of N-acetylphenothiazine by fungi. Appl Microbiol Biotechnol 52, 553–557 (1999). https://doi.org/10.1007/s002530051559
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DOI: https://doi.org/10.1007/s002530051559