Abstract.
Host-parasite relationships represent integrating adaptations of considerable complexity involving the host's immune capacity to both recognize and destroy the parasite, and the latter's ability to successfully invade the host and to circumvent its immune response. Compatibility in Drosophila-parasitic wasp (parasitoid) associations has been shown to have a genetic basis, and to be both species and strain specific. Studies using resistant and susceptible strains of Drosophila melanogaster infected with virulent and avirulent strains of the wasp Leptopilina boulardi demonstrate that the success of the host cellular immune response depends on the genetic status of both host and parasitoid. Immunological, physiological, biochemical, and genetic data form the bases of a two-component model proposed here to account for the observed specificity and complexity of two co-evolved adaptations, host nonself recognition and parasitoid virulence.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
Author information
Authors and Affiliations
Additional information
Electronic Publication
Rights and permissions
About this article
Cite this article
Carton, Y., Nappi, A. Immunogenetic aspects of the cellular immune response of Drosophila against parasitoids. Immunogenetics 52, 157–164 (2001). https://doi.org/10.1007/s002510000272
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s002510000272