Abstract
Accurate diagnosis of non-accidental injury (NAI) can be reached in the majority of cases by careful appraisal of the social and family history, combined with painstaking clinical roentgenographic and other imaging evaluations. Careful review of the scientific literature clearly indicates that collagen analysis to exclude mild forms of osteogenesis imperfecta, especially type IV, is recommended only in rare cases in which diagnosis of NAI remains in doubt even after thorough evaluation by experienced radiologists and/or other physicians. Until clinical research scientifically establishes the existence of temporary brittle bone disease, it should remain strictly a hypothetical entity and not an acceptable medical diagnosis.
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Kleinman PK (1987) Diagnostic imaging of child abuse. Williams & Wilkins, Baltimore
Ablin DS, Greenspan A, Reinhart M, Grix A (1990) Differentiation of child abuse from osteogenesis imperfecta. AJR 154: 1035–1046
Ablin DS, Greenspan A, Reinhart M, Grix A (1990) Differentiation of child abuse from osteogenesis imperfecta. (Letter) AJR 155: 1347
Carty H (1991) Differentiation of child abuse from osteogenesis imperfecta. (Letter) AJR 156: 635
Paterson CR, Burns J, McAllion SJ (1993) Osteogenesis imperfecta: the distinction from child abuse and the recognition of a variant form. Am J Med Genet 45: 187–192
Byers P (1993) Papers presented at the Fourth International Conference on Osteogenesis Imperfecta: introduction. Am J Med Genet 45: 139
Wall J (1995) Re AB (Child abuse: expert witnesses). FLR 1: 181–200 (Fam Div)
Lynch MA (1995) A judicial comment on temporary brittle bone disease. (Letter) Arch Dis Child 73: 379
Taitz LS (1988) Child abuse and osteogenesis imperfecta. (Letter) Br Med J 296: 292
Paterson CR, Burns J, McAllion SJ (1995) Osteogenesis imperfecta variant vs child abuse. (Reply) Am J Med Genet 56: 117–118
Kleinman PK, Marks SC, Adam VI, Blackbourne BD (1988) Factors affecting visualization of posterior rib fractures in abused children. AJR 150: 635–638
Sillence DO, Senn A, Danks DM (1979) Genetic heterogeneity in osteogenesis imperfecta. J Med Genet 16: 101–116
Taitz LS (1987) Child abuse and osteogenesis imperfecta. (Letter) Br Med J 295: 1082–1083
Wenstrup RJ, Willing MC, Starman BJ, Byers PH (1990) Distinct biochemical phenotypes predict clinical severity in nonlethal variants of osteogenesis imperfecta. Am J Hum Genet 46: 975–982
Steiner RD, Pepin M, Byers PH (1996) Studies of collagen synthesis and structure in the differentiation of child abuse from osteogenesis imperfecta. J Pediatrics 128: 542–547
Knight DJ, Bennet GC (1990) Nonaccidental injury in osteogenesis imperfecta: a case report. J Pediatr Orthop 10: 542–544
Kasim MS, Cheah I, Sameon H (1995) Osteogenesis imperfecta and non-accidental injury: problems in diagnosis and management. Med J Malaysia 50: 170–175
Anonymous (1996) Child maltreatment 1994: reports from the states to the National Center on Child Abuse and Neglect. National Center on Child Abuse and Neglect, US Government Printing Office, Washington, DC
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Ablin, D.S., Sane, S.M. Non-accidental injury: confusion with temporary brittle bone disease and mild osteogenesis imperfecta. Pediatr Radiol 27, 111–113 (1997). https://doi.org/10.1007/s002470050079
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DOI: https://doi.org/10.1007/s002470050079