Abstract
Different veniafaxine doses (1, 5, and 10 mg/kg) and saline solution were administered to ten male Wistar rats (Latin-Square design). Compared with saline, veniafaxine produced a dose-related supression of REM sleep and an increase in wake time while slow wave sleep was reduced. This effect is similar to the one that has been reported with some tricyclic antidepressants.
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Salin-Pascual, R.J., Moro-Lopez, M.L. Effects of veniafaxine in the sleep architecture of rats. Psychopharmacology 129, 295–296 (1997). https://doi.org/10.1007/s002130050194
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DOI: https://doi.org/10.1007/s002130050194