Abstract
The possibility to determine the relatively small organic compound conformations by the approach on the basis of the analysis of the residual dipolar couplings1H−13C in the molecules partially aligned in lyotropic liquid crystalline media has been considered. This approach has been used in the nuclear magnetic resonance investigation of the triglycine structure in lyotropic medium (cetylpyridinium bromide/n-hexanol). The conformation of triglycine in solution has been established astrans-trans on the basis of the experimental data of observed couplings.
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References
Jackman L.M., Cotton F.A. (eds.): Dynamic Nuclear Magnetic Resonance Spectroscopy, part 1, p. 660. New York: Academic Press 1975; Sandstrom J.: Dynamic NMR Spectroscopy, p. 226. London: Academic Press 1982.
Oki M.: Application of Dynamic NMR Spectroscopy to Organic Chemistry, p. 423. New York: VCH Publishers 1985.
Ernst R.R., Bodenhausen B., Wokaun A.: Principles of Nuclear Magnetic Resonance in One and Two Dimensions, p. 610. Oxford: Oxford University Press 1987.
Van der Ven F.J.M.: Multidimensional NMR in Liquids: Basic Principles and Experimental Methods, p. 399. New York: Wiley-VCH 1995.
Tjandra N., Bax A.: Science278, 1111–1114 (1997)
Alba E., Tjandra N.: Prog. NMR Spectrosc.40, 175–197 (2002)
Shakhatuni A.A., Shakhatuni A.G.: Usp. Khim.71, 1132–1172 (2002)
Barrientos L.G., Dolan C., Gronenborn A.M.: J. Biomol. NMR16, 329–337 (2000)
Clore G.M., Starich M.R., Gronenborn A.M.: J. Am. Chem. Soc.120, 10571–10572 (1998)
Koenig B.W., Hu J., Ottiger M., Bose S., Hendler R.W., Bax A.: J. Am. Chem. Soc.121, 1385–1386 (1999)
Prosser R.S., Losonczi J.A., Shiyanovskaya I.V.: J. Am. Chem. Soc.120, 11010–11011 (1998)
Ruckert M., Otting G.: J. Am. Chem. Soc.122, 7793–7797 (2000)
Kim M.K., Martell A.E.: J. Am. Chem. Soc.91, 872–878 (1969)
Bradley E.K., Kerr J.M., Richter L.S., Figliozzi G.M., Goff D.A., Zuckermann R.N., Spellmeyer D.C., Blaney J.M.: Mol. Divers.3, 1–15 (1997)
Anishetty S., Pennathur G., Anishetty R.: BMC Struct. Biol.2, 9 (2002)
Wüthrich K.: NMR of Proteins and Nucleic Acids, p. 292. New York: Wiley-VCH 1986.
Breitmaier E., Woelter W.:13C NMR Spectroscopy: Methods and Application in Organic Chemistry, p. 322. Weinheim: Verlag Chemie 1978.
Dosset P., Hus J.-C., Blackledge M.: J. Biomol. NMR20, 223–233 (2001)
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Klochkov, V.V., Khairutdinov, B.I., Klochkov, A.V. et al. Spatial structure of triglycine determined by the residual dipolar coupling analysis. Appl. Magn. Reson. 25, 113–119 (2003). https://doi.org/10.1007/BF03166971
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DOI: https://doi.org/10.1007/BF03166971