Abstract
Callous and unemotional (CU) traits provide researchers and clinicians with an additional dimension when assessing children displaying early-onset conduct problems. Evidence from genetic, brain and cognitive studies to date suggests that antisocial children with psychopathic personality traits are genetically more vulnerable to antisocial behaviour than their antisocial peers. Neuroimaging studies in adults with psychopathy have demonstrated amygdala hyporeactivity to emotional stimuli, while there is some suggestion that adults with antisocial behaviour but no psychopathy may show the opposite pattern. Child neuroimaging data in this area are still thin on the ground; however, behavioural data support the hypothesis that antisocial children with callous-unemotional traits may have some amygdala abnormality. When compared with each other, antisocial children with callous-unemotional traits demonstrate hyposensitivity to others’ distress, while other antisocial children appear hypersensitive to anger directed towards them. New research combining different levels of analyses will no doubt provide further insight about the distinct developmental patterns associated with psychopathy, and help to inform methods of intervention, allowing treatment of antisocial behaviour to be targeted according to whether elevated levels of CU traits are present. (Netherlands Journal of Psychology, 63, 117-125.)
Notes
Please note that we use the terms CU and psychopathic personality interchangeably in this review.
References
Andershed, H., Gustafson, S.B., Kerr, M. & Stattin, H. (2002). The usefulness of self-reported psychopathy-like traits in the study of antisocial behaviour among non-referred adolescents European Journal of Personality, 16, 383-402.
Baron-Cohen, S. (1995). Mindblindness: an essay on autism and theory of mind: MA: MIT Press.
Baron-Cohen, S., Leslie, A.M. & Frith, U. (1985). Does the autistic child have a 'theory of mind'? Cognition, 21, 37-46.
Barry, C.T., Frick, P.J., DeShazo, T.M., McCoy, M.G., Ellis, M. & Loney, B.R. (2000). The importance of callous-unemotional traits for extending the concept of psychopathy to children. Journal of Abnormal Psychology, 109, 335-340.
Birbaumer, N., Veit, R., Lotze, M., Erb, M., Hermann, C., Grodd, W., et al. (2005). Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study. Archives of General Psychiatry, 62, 799-805.
Blair, R.J.R. (2006). The emergence of psychopathy: Implications for the neuropsychological approach to developmental disorders. Cognition, 101, 414-442.
Blair, R.J.R., Peschardt, K.S., Budhani, S., Mitchell, D.G.V. & Pine, D.S. (2006). The development of Psychopathy. Journal of Child Psychology & Psychiatry, 47, 262-275.
Blonigen, D.M., Hicks, B.M., Krueger, R.F., Patrick, C.J. & Iacono, W.G. (2005). Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology. Psychological Medicine, 35, 637-648.
Caspi, A., McClay, J., Moffitt, T., Mill, J., Martin, J., Craig, I.W., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851-854.
Cleckley, H. (1976). The Mask of Sanity (5th Edition). St Louis, MO: Mosby.
Cloninger, C. (1978). The link between hysteria and sociopathy: An integrative model of pathogenesis based on clinical, genetic, and neurophysiological observations. In H.S. Akiskal & W.L. Webb (Eds.), Psychiatric diagnosis: Exploration of biological predictors (pp. 189-218). New York: Spectrum.
Dadds, M.R., Fraser, J., Frost, A. & Hawes, D.J. (2005). Disentangling the underlying dimensions of psychopathy and conduct problems in childhood: A community study. Journal of Consulting & Clinical Psychology, 73, 400-410.
Dadds, M.R., Perry, Y., Hawes, D.J., Merz, S., Riddell, A.C., Haines, D.J., et al. (2006). Attention to the eyes and fear-recognition deficits in child psychopathy. British Journal of Psychiatry, 189, 280-281.
Davidson, R.J., Putnam, K.M. & Larson, C.L. (2000). Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence. Science, 289, 591-594.
Deeley, Q., Daly, E., Surguladze, S., Tunstall, N., Mezey, G., Beer, D., et al. (2006). Facial emotion processing in criminal psychopathy. Preliminary functional magnetic resonance imaging study. British Journal of Psychiatry, 189, 533-539.
Eckenrode, J., Zielinski, D., Smith, E., Marcynyszyn, L.A., Henderson, C.R., Jr., Kitzman, H., et al. (2001). Child maltreatment and the early onset of problem behaviors: can a program of nurse home visitation break the link? Developmental Psychopathology, 13, 873-890.
Eisenberger, N.I., Way, B.M., Taylor, S.E., Welch, W.T. & Lieberman, M.D. (2007). Understanding Genetic Risk for Aggression: Clues From the Brain's Response to Social Exclusion. Biological Psychiatry, 35, 1601-1612.
Forth, A.E., Kosson, D.S. & Hare, R.D. (2003). The Psychopathy Checklist: Youth Version. Toronto, Ontario: Multi-Health Systems.
Frick, P.J. (2001). Effective interventions for children and adolescents with conduct disorder. Canadian Journal of Psychiatry, 46, 597-608.
Frick, P.J., Cornell, A.H., Bodin, S., Dane, H.E., Barry, C.T. & Loney, B.R. (2003). Callous-unemotional traits and developmental pathways to severe conduct problems. Developmental Psychology, 39, 246-260.
Frick, P.J. & Hare, R.D. (2001). Antisocial Process Screening Device. Toronto: Multi Health Systems.
Frick, P.J. & Marsee, M.A. (2006). Psychopathy and Developmental Pathways to Antisocial Behavior in Youth. In C.J. Patrick (Ed.), Handbook of Psychopathy. New York: Guilford.
Frick, P.J., Stickle, T.R., Dandreaux, D.M., Farrell, J.M. & Kimonis, E.R. (2005). Callous-unemotional traits in predicting the severity and stability of conduct problems and delinquency. Journal of Abnormal Child Psychology, 33, 471-487.
Hare, R.D. (1991). The Hare Psychopathy Checklist - Revised. Toronto, Ontario: Multi-Health Systems.
Hare, RD. & Neumann, C.S. (2005). Structural models of psychopathy. Current Psychiatry Reports 7(1), 57-64.
Hart, S.D., Cox, D.N. & Hare, R.D. (1995). Manual for the Psychopathy Checklist: Screening Version (PCL:SV). Toronto, Canada: Multi-Health Systems.
Hart, S.D. & Hare, R.D. (1997). Psychopathy: Assessment and association with criminal conduct. In D. Stoff, J. Breiling, & J. Maser (Eds.), Handbook of Antisocial Behaviour (pp. 22-35). New York, NY, US: John Wiley & Sons, Inc.
Hawes, D.J. & Dadds, M.R. (2005). The treatment of conduct problems in children with callous-unemotional traits. Journal of Consulting & Clinical Psychology, 73, 737-741.
Kiehl, K.A., Smith, A.M., Hare, R.D., Mendrek, A., Forster, B.B., Brink, J., et al. (2001). Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance imaging. Biological Psychiatry, 50, 677-684.
Kim-Cohen, J., Caspi A, Taylor A, Williams B, Newcombe R, Craig I.W, et al. (2006). MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. Molecular Psychiatry, 11, 903-913.
Larsson, H., Viding, E. & Plomin, R. (in press). Callous-unemotional traits and antisocial behaviour: Genetic, environmental and early childhood influences. Criminal Justice & Behavior.
Lesch, K.P. (2003). The serotonergic dimension of aggression and violence. In M. P. Mattson (Ed.), Neurobiology of Aggression. Totowa, NJ: Humana Press.
Levenson, M.R., Kiehl, K.A. & Fitzpatrick, C.M. (1995). Assessing psychopathic attributes in a non-institutionalized population. Journal of Personality and Social Psychology, 68, 151-158.
Lilienfeld, S.O. & Andrews, B.P. (1996). Development and preliminary validation of a self-report measure of psychopathic personality. Journal of Personality Assessment, 66, 488-524.
Loeber, R., Burke, J.D. & Lahey, B.B. (2002). What are adolescent antecedents to antisocial personality disorder? Criminal Behaviour & Mental Health, 12, 24-36.
Loney, B.R., Frick, P.J., Clements, C.B., Ellis, M.L. & Kerlin, K. (2003). Callous-unemotional traits, impulsivity, and emotional processing in adolescents with antisocial behavior problems. Journal of Clinical Child & Adolescent Psychology, 32, 66-80.
Manuck, S.B., Flory, J.D., Ferrell, R.E., Dent, K.M., Mann, J.J. & Muldoon, M.F. (1999). Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene. Biological Psychiatry, 45, 603-614.
Meyer-Lindenberg, A., Buckholtz, J.W., Kolachana, B., Hariri, A.R., Pezawas, L., Blasi, G., et al. (2006). Neural mechanisms of genetic risk for impulsivity and violence in humans. Proceedings of the National Academy of Sciences of the United States of America, 103, 6269-6274.
Meyer-Lindenberg, A. & Weinberger, D. (2006). Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nature Review Neuroscience, 7, 818-827.
Moffitt, T., Caspi, A. & Rutter, M. (2005). Strategy for investigating interactions between measured genes and measured environments. Archives of General Psychiatry, 62, 473-481.
National Council of Bioethics, (2002). Genetics and Human Behaviour: the Ethical Context. London, UK.
Olds, D.L., Eckenrode, J., Henderson, C.R., Jr., Kitzman, H., Powers, J., Cole, R., et al. (1997). Long-term effects of home visitation on maternal life course and child abuse and neglect. Fifteen-year follow-up of a randomized trial. Journal of the American Medical Association, 278, 637-643.
Oxford, M., Cavell, T. & Hughes, J. (2003). Callous-unemotional traits moderate the relation between ineffective parenting and child externalizing problems: A partial replication and extension. Journal of Clinical Child & Adolescent Psychology, 32, 577-585.
Pardini, D.A., Lochman, J.E. & Frick, P.J. (2003). Callous/unemotional traits and social-cognitive processes in adjudicated youths. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 364-371.
Plomin, R. (1994). Genetics and experience: The interplay between nature and nurture: (1994). Newbury Park, CA: Sage Publications; xvi, 189 pp.
Plomin, R., DeFries, J., McClearn, G. & McGuffin, P. (2000). Behavioral Genetics (4th ed.). New York, US: Worth Publishers.
Plomin, R., Owen, M.J. & McGuffin, P. (1994). The genetic basis of complex human behaviors. Science, 264, 1733-1739.
Pollak, S.D. & Sinha, P. (2002). Effects of early experience on children's recognition of facial displays of emotion. Developmental Psychology, 38, 784-791.
Rhee, S.H. & Waldman, I.D. (2002). Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies. Psychological Bulletin, 128, 490-529.
Spitzer, R.L., Endicott, J. & Robins, E. (1975). Clinical criteria for psychiatric diagnosis and DSM-III. American Journal of Psychiatry, 132, 1187-1192.
Sterzer, P., Stadler, C., Krebs, A., Kleinschmidt, A. & Poutska, F. (2005). Abnormal neural response to emotional visual stimuli in adolescents with conduct disorder. Biological Psychiatry, 57, 7-15.
Taylor, J., Loney, B.R., Bobadilla, L., Lacono, W.G. & McGue, M. (2003). Genetic and environmental influences on psychopathy trait dimensions in a community sample of male twins. Journal of Abnormal Child Psychology, 31, 633-645.
Viding, E., Blair, R.J.R., Moffitt, T.E. & Plomin, R. (2005). Evidence for substantial genetic risk for psychopathy in 7-year-olds. Journal of Child Psychology & Psychiatry, 46, 592-597.
Viding, E., & Frith, U. (2006). Genes for susceptibility to violence lurk in the brain. Proceedings of the National Academy of Sciences of the United States of America, 103, 6085-6086.
Viding, E., Jones, A., Frick, P., Moffit, T.E. & Plomin, R. (in press). Genetic and phenotypic investigation to early risk factors for conduct problems in children with and without psychopathic tendencies. Developmental Science.
Wootton, J.M., Frick, P.J., Shelton, K.K. & Silverthorn, P. (1997). Ineffective parenting and childhood conduct problems: The moderating role of callous-unemotional traits. Journal of Consulting & Clinical Psychology, 65, 301-308.
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Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, UK and
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, and Department of Psychology and Institute of Cognitive Neuroscience, University College London, UK Correspondence to: Essi Viding, Department of Psychology, University College London, Gower St., London, WC1E 6BT, UK, e-mail: e.viding@ucl.ac.ukSubmitted 22 March 2007; revision accepted 27 July 2007.
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Jones, A.P., Viding, E. Psychopathic traits in young children. NEJP 63, 107–114 (2007). https://doi.org/10.1007/BF03061073
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DOI: https://doi.org/10.1007/BF03061073