Summary and Conclusions
Plasma free Cortisol levels were measured in 47 patients. Seven patients served as a control group. Twenty patients received spinal anaesthesia with the newly synthetized short-acting quatacain (Tanacaine), and the remaining 20 underwent spinal anaesthesia with lidocaine ( Xylocaine ). There was no significant influence on the plasma free Cortisol levels in the 40 patients during spinal anaesthesia before operation. However, plasma Cortisol increased significantly during operation, although the magnitude of the elevation was less than during general anaesthesia.
Résumé
Nous avons mesuré, chez 47 malades, les taux de Cortisol plasmatique libre. Sept malades ont servi de groupe témoin. Vingt malades ont reçu une rachianesthésie avec le nouvel agent synthétique à action courte: quatacaine (Tanacaine) et les vingt autres ont eu une rachianesthésie avec de la lidocaïne (Xylocaine). Avant ľopération, nous n’avons pas observé de modification importante des taux de Cortisol plasmatique libre chez les quarante malades sous rachianesthésie. Pendant ľopération, toutefois, le Cortisol plasmatique a augmenté de façon appréciable. Toutefois, ľimportance de ľaugmentation du taux de Cortisol plasmatique est demeurée inférieure à celle observée au cours de ľanesthésie générale.
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Oyama, T., Matsuki, A. Plasma levels of cortisol in man during spinal anaesthesia and surgery. Can. Anaesth. Soc. J. 17, 234–241 (1970). https://doi.org/10.1007/BF03004601
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DOI: https://doi.org/10.1007/BF03004601